Major and minor salivary gland cancers: A multicenter retrospective study

• Published in: Head & neck 2023-07, Vol.45 (7), p.1643-1653
• Main Authors: Hacioglu, Muhammet Bekir, Erdogan, Bulent, Bardakcı, Murat, Algın, Efnan, Gulbagcı, Burcu, Hacibekiroglu, Ilhan, Hamdard, Jamshid, Olmez, Omer Fatih, Akkus, Hadi, Oksuzoglu, Berna, Goksu, Sema Sezgin, Dae, Shute Ailia, Sumbul, Ahmet Taner, Ugraklı, Muzaffer, Karaagac, Mustafa, Sahin, Elif, Cabuk, Devrim, Ozer, Ozden, Yavuzsen, Tugba, Arıkan, Rukiye, Köstek, Osman, Atcı, Muhammed Mustafa, Sakin, Abdullah, Deligonul, Adem, Bayır, Duygu, Dincer, Murat, Unsal, Oktay, Yazıcı, Ozan, Zeynelgil, Esra, Gulmez, Ahmet, Harputluoglu, Hakan, Erol, Cihan, Sendur, Mehmet Ali Nahit, Aytekin, Aydin, Akagunduz, Baran, Oner, Irem, Er, Ozlem, Oztosun, Bugra, Gumus, Mahmut, Selçukbiricik, Fatih, Aykan, Musa Baris, Karadurmus, Nuri, Degerli, Ezgi, Demirci, Nebi Serkan, Turkmen, Esma, Şakalar, Teoman, Secmeler, Saban, Tanrıverdi, Ozgur, Alkan, Ali, Kemal, Yasemin, Cil, Ibrahim, Unal, Caglar, Iriagaç, Yakup, Alan, Ozkan, Balli, Sevinc, Urun, Yuksel, Ozcan, Erkan, Turhal, Nazım Serdar, Cicin, Irfan
• Format: Article
• Language: English
• Subjects: Epidemiology; histopathology; incidence; major salivary gland; Metastases; minor salivary gland; Oral cancer; Patients; Salivary gland; salivary gland cancers
• ISSN: 1043-3074; 1097-0347
• DOI: 10.1002/hed.27376

Background Most of the studies on salivary gland cancers are limited for various reasons such as being single‐center, small number of patients, including only major or minor SGCs, or only including epidemiological data. Methods A total of 37 medical oncology clinics from different regions of Turkey participated in this retrospective‐multicenter study. The analyzed data included clinical and demographical features, primary treatment, metastasis localizations, and treatments and includes certain pathologic features. Results The study included data from a total of 443 SGCs. 56.7% was in major salivary glands and 43.3% was in minor salivary glands. Distant metastasis in the major SGCs was statistically significantly more common than in the minor SGCs, locoregional recurrence was statistically significantly more common in the minor SGCs than in the major SGCs (p = 0.003). Conclusions Epidemiological information, metastasis and recurrence patterns, treatment modalities, and survival analysis of the patients over 20 years of follow‐up are presented.