Elevated neutrophil-related immune-inflammatory biomarkers in acute anterior choroidal artery territory infarction with early progression

The anterior choroidal artery territory (AChA) infarction has a high rate of progression and poor functional prognosis. The aim of the study is to search for fast and convenient biomarkers to forecast the early progression of acute AChA infarction. We respectively collected 51 acute AChA infarction...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2023-06, Vol.229, p.107720-107720, Article 107720
Main Authors: Zhao, Ning, Li, Jia, Zhang, Qiu-Xia, Yang, Li, Zhang, Lin-Jie
Format: Article
Language:English
Subjects:
Anterior choroidal artery
Arteries
Autoimmune diseases
Biomarkers
Blood tests
Cardiac arrhythmia
Cardiovascular disease
Cerebral Infarction
Cholesterol
Early progression
High density lipoprotein
Hospitalization
Hospitals
Humans
Hyperlipidemia
Hypertension
Infarction
Inflammation
Leukocytes
Leukocytes (neutrophilic)
Lipoproteins
Lipoproteins, HDL
Lymphocytes
Medical imaging
Monocytes
Neurology
Neutrophil to high-density lipoprotein cholesterol ratio
Neutrophil to lymphocyte ratio
Neutrophils
Prognosis
Retrospective Studies
ROC Curve
Statistical analysis
Stroke
Vein & artery diseases
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Summary:The anterior choroidal artery territory (AChA) infarction has a high rate of progression and poor functional prognosis. The aim of the study is to search for fast and convenient biomarkers to forecast the early progression of acute AChA infarction. We respectively collected 51 acute AChA infarction patients, and compared the laboratorial index between early progressive and non-progressive acute AChA infarction patients. The receiver-operating characteristics curve (ROC) analysis was used to determine the discriminant efficacy of indicators that had statistical significance. The white blood cell, neutrophil, monocyte, white blood cell to high-density lipoprotein cholesterol ratio, neutrophil to high-density lipoprotein cholesterol ratio (NHR), monocyte to high-density lipoprotein cholesterol ratio, monocyte to lymphocyte ratio, neutrophil to lymphocyte ratio (NLR), and hypersensitive C-reaction protein in acute AChA infarction are significantly higher than healthy controls (P 
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2023.107720