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Predictors of Adverse Outcome in High-Risk Percutaneous Coronary Interventions Patients

Identifying high-risk percutaneous coronary intervention (PCI) patients is challenging. We aimed to evaluate which high-risk patients are prone to adverse events. We performed a retrospective study including consecutive high-risk PCIs from 2005 to 2018 in a large tertiary medical centre. Patients wi...

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Bibliographic Details
Published in:Canadian journal of cardiology 2023-10, Vol.39 (10), p.1369-1379
Main Authors: Peles, Ido, Barrett, Orit, Cafri, Carlos, Garcia-Garcia, Hector, Tsaban, Gal, El-Nasasra, Aref, Abramowitz, Yigal, Shmueli, Hezzy, Rosenstein, Gabriel, Merkin, Miri, Zahger, Doron, Koifman, Edward
Format: Article
Language:English
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Summary:Identifying high-risk percutaneous coronary intervention (PCI) patients is challenging. We aimed to evaluate which high-risk patients are prone to adverse events. We performed a retrospective study including consecutive high-risk PCIs from 2005 to 2018 in a large tertiary medical centre. Patients with unprotected left main (LM) disease, last patent coronary vessel, or 3-vessel coronary artery disease with left ventricular ejection fraction < 35% were included. A predictive 30-day major adverse cardiac events (MACE) score consisting of any myocardial infarction, all-cause death, or target-vessel revascularisation was constructed. From 2005 to 2018, a total of 1890 patients who underwent PCI met the predefined high-risk PCI criteria. Mortality rate was 8.8% at 30 days and 20.7% at 1 year, and 30-day MACE rate was 14.2% and 33.5% at 1 year. Predictors of short-term MACE were New York Heart Association functional class (NYHA) 4 (hazard ratio [HR] 6.65; P  50 mm Hg (HR 2.06; P 
ISSN:0828-282X
1916-7075
DOI:10.1016/j.cjca.2023.04.021