Systemic Therapy in Elderly Patients With Her2/Neu-Positive Breast Cancer: A SEER Database Study

Background The use of systemic therapy in elderly patients with Her2/neu-positive breast cancers has been questioned given the potential for cardiac side effects with several of the agents frequently used. This study aimed to evaluate trends in use of systemic therapy in patients 70 years and older....

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Bibliographic Details
Published in:The American surgeon 2023-12, Vol.89 (12), p.5690-5696
Main Authors: Wilbers, Ashley, Quinn, Karson R., Okut, Hayrettin, Helmer, Stephen D., Tenofsky, Patty L.
Format: Article
Language:English
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Summary:Background The use of systemic therapy in elderly patients with Her2/neu-positive breast cancers has been questioned given the potential for cardiac side effects with several of the agents frequently used. This study aimed to evaluate trends in use of systemic therapy in patients 70 years and older. Methods The 2010-2016 SEER database was used to collect data on female patients with non-metastatic Her2/neu-positive breast cancer. Data was stratified to compare systemic therapy use in patients
ISSN:0003-1348
1555-9823
DOI:10.1177/00031348231173993