Analysis of risk factors for recurrence of differentiated thyroid carcinoma after surgical resection combined with iodine-131 and TSH suppression therapy

• Published in: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery head, and neck surgery, 2023-05, Vol.37 (5), p.370
• Main Authors: Ye, Ting, Lai, Shengwei, Cao, Baolin, Xu, Baixuan, Wang, Ruimin
• Format: Article
• Language: Chinese
• Subjects: Adenocarcinoma; Humans; Lymph Nodes - pathology; Lymphatic Metastasis - pathology; Neck Dissection; Neoplasm Recurrence, Local - pathology; Retrospective Studies; Risk Factors; Thyroid Cancer, Papillary - surgery; Thyroid Neoplasms - surgery; Thyroidectomy - adverse effects; Thyrotropin
• ISSN: 2096-7993
• DOI: 10.13201/j.issn.2096-7993.2023.05.010

To investigate the risk factors of recurrence after surgical resection of differentiated thyroid carcinoma combined with iodine-131 and TSH（Thyroid stimulating hormone） inhibition therapy. From January 2015 to April 2020, the clinical data of patients with structural recurrence and without recurrence were retrospectively collected after surgical treatment combined with iodine-131 and TSH inhibition therapy in the First Medical Center of PLA General Hospital. The general conditions of the two groups of patients were analyzed and the measurement data in line with the normal distribution was used for comparison between groups. For measurement data with non-normal distribution, the rank sum test was used for inter-group comparison. The Chi-square test was used for comparison between the counting data groups. Univariate and multivariate regression analyses were used to determine the risk factors associated with relapse. The median follow-up period was 43 months（range 18-81 months） and 100 patients（10.5%） relapsed