A review of the current management and burden of prurigo nodularis in the United States

Prurigo nodularis (PN) is a chronic neural- and immune-mediated disease that is characterized by intense itch, history of skin scratching, and development of papulonodular lesions. These lesions can develop consequent to a cycle of itching and scratching associated with inflammation and changes in s...

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Bibliographic Details
Published in:The American journal of managed care 2023-05, Vol.29 (5 Suppl), p.S63-S72
Main Author: Chisolm, Sarah S
Format: Article
Language:English
Subjects:
Adult
Dermatitis, Atopic
Female
Humans
Middle Aged
Prurigo - diagnosis
Prurigo - epidemiology
Prurigo - therapy
Pruritus - epidemiology
Pruritus - etiology
Pruritus - pathology
Quality of Life
Skin
United States - epidemiology
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Summary:Prurigo nodularis (PN) is a chronic neural- and immune-mediated disease that is characterized by intense itch, history of skin scratching, and development of papulonodular lesions. These lesions can develop consequent to a cycle of itching and scratching associated with inflammation and changes in skin cells and nerve fibers (eg, pathogenic skin fibrosis, tissue remodeling, and chronic neuronal sensitization). Diagnosis of PN involves individual evaluation of clinical characteristics to identify disease and symptom severity. In the United States, adult patients with PN (estimated, 
ISSN:1088-0224
1936-2692
DOI:10.37765/AJMC.2023.89366