Target-Responsive Metal–Organic Framework Nanosystem with Synergetic Sensitive Detection and Controllable Degradation against the Pesticide Triazophos in Contaminated Samples for Environment Assessment and Food Safety

• Published in: ACS applied materials & interfaces 2023-05, Vol.15 (19), p.23783-23791
• Main Authors: Liu, Jintong, Mo, Yan Yang, Zhang, Heng, Tang, Jie, Bao, Han, Wei, Liuyu, Yang, Hong
• Format: Article
• Language: English
• Subjects: Applications of Polymer, Composite, and Coating Materials; Food Safety; Metal-Organic Frameworks; Pesticide Residues - analysis; Pesticides
• ISSN: 1944-8244; 1944-8252
• DOI: 10.1021/acsami.3c03248

Developing sensitive practical sensors for monitoring pesticide residues in edible foods and environmental samples is vital for food safety and environmental protection. Enzyme-inhibited biosensors offer effective alternative sensing strategies by using the inherent characteristics of pesticides. To further improve the degradation function of pesticide sensors, here, a target-triggered porphyrin metal–organic framework (MOF)-based nanosystem was designed with the synergetic bifunction of sensitive detection and controllable degradation of the triazophos pesticide. As a result of triazophos-inhibited glutathione consumption, the MOF collapsed and released the ligand porphyrin, leading to the recovery of fluorescence and photosensitization of the free porphyrin. The fluorescence recovery resulted in a sensitive detection limit of 0.6 ng mL–1 for triazophos, which was also applied for the determination of contaminated samples and bioaccumulation in rice. Furthermore, the target-activated photocatalytic ability of porphyrin endowed the system with the ability to effectively generate reactive oxygen species for degrading triazophos with a removal rate of ∼85%, achieving eco-friendly synergetic detection and photodegradation in a controllable way. Therefore, the intelligent multifunctional MOF system demonstrated the potential of programmable systems for jointly controllable tracking and elimination of pesticide residues in the environment and opened a new avenue for designing a precise mechanism for stimulus-triggered degradation of pesticide residues accompanied by sensitive detection for environmental friendliness and food safety.