Dietary flaxseed (Linum usitatissimum) oil supplementation affects growth, oxidative stress, immune response, and diseases resistance in rainbow trout (Oncorhynchusmykiss)

This paper describes the effects of flaxseed (Linum usitatissimum) oil (FSO) as a feed additive on growth performance, oxidative stress, immunity, and disease resistance in rainbow trout (Oncorhynchus mykiss). Eight-hundred-and-forty rainbow trout individuals (mean weight: 25.66 ± 1.33 g) were fed w...

Full description

Saved in:
Bibliographic Details
Published in:Fish & shellfish immunology 2023-07, Vol.138, p.108798-108798, Article 108798
Main Authors: Salem, Mohamed Omar Abdalla, Taştan, Yiğit, Bilen, Soner, Terzi, Ertugrul, Sönmez, Adem Yavuz
Format: Article
Language:English
Subjects:
Feed additive
Growth promoter
Immunostimulant
Natural product
Plant oil
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c353t-c29d480749eb74607ab50b1f1b03c41fcb3abf91ee007f57beebc9087b97b5613
cites cdi_FETCH-LOGICAL-c353t-c29d480749eb74607ab50b1f1b03c41fcb3abf91ee007f57beebc9087b97b5613
container_end_page 108798
container_issue
container_start_page 108798
container_title Fish & shellfish immunology
container_volume 138
creator Salem, Mohamed Omar Abdalla
Taştan, Yiğit
Bilen, Soner
Terzi, Ertugrul
Sönmez, Adem Yavuz
description This paper describes the effects of flaxseed (Linum usitatissimum) oil (FSO) as a feed additive on growth performance, oxidative stress, immunity, and disease resistance in rainbow trout (Oncorhynchus mykiss). Eight-hundred-and-forty rainbow trout individuals (mean weight: 25.66 ± 1.33 g) were fed with different doses of FSO (0.5, 1, and 1.5%) ad libitum two times a day for 9 weeks. At the end of the feeding, growth performance was evaluated and the fish were challenged with two different bacteria (Yersinia ruckeri and Aeromonas hydrophila). At the end of the 3rd, 6th, and 9th weeks, blood and tissue samples were taken from 9 fish per treatment to evaluate innate immune response, cytokine gene expression levels, antioxidant enzyme activities and lipid peroxidation levels, and digestive enzyme activities. Determination of haematological parameters and histological examination was also carried out to evaluate the general health status of the fish. Results showed that the final weight and specific growth rate of FSO-supplemented fish increased significantly (p 
doi_str_mv 10.1016/j.fsi.2023.108798
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2811215834</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S105046482300284X</els_id><sourcerecordid>2811215834</sourcerecordid><originalsourceid>FETCH-LOGICAL-c353t-c29d480749eb74607ab50b1f1b03c41fcb3abf91ee007f57beebc9087b97b5613</originalsourceid><addsrcrecordid>eNp9UcuO1DAQjBCIXRY-gAvycVaaDHZeTsQJLU9ppL3A2bKdDuMhtoPb3t35Jn4SR7Nw5NTd7qpSu6ooXjO6Y5R1b4-7Cc2uolWd554P_ZPiktGhLYeh4U_XvqVl0zX9RfEC8Ugp7eqOPi8uas7azOKXxe8PBqIMJzLN8gEBRrLZG5csSWiijAbR2GSviTczwbQsM1hw68I7IqcJdETyI_j7eNgS_2DGvLkDgjEA4pYYa5MDkofFO4QtkW4ko0GQCLg-G4zSaSDGkSCNU_6exOBTJJtbp304nJw-JLSnn_mQ65fFs0nOCK8e61Xx_dPHbzdfyv3t56837_elrts6lroaxqanvBlA8aajXKqWKjYxRWvdsEmrWqppYACU8qnlCkDpIfunBq7ajtVXxeasuwT_KwFGYQ1qmGfpwCcUVc9Yxdq-bjKUnaE6eMQAk1iCsdlPwahYMxJHkTMSa0binFHmvHmUT8rC-I_xN5QMeHcGQP7knYEgUBvINo0mZMPF6M1_5P8AOjunFQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2811215834</pqid></control><display><type>article</type><title>Dietary flaxseed (Linum usitatissimum) oil supplementation affects growth, oxidative stress, immune response, and diseases resistance in rainbow trout (Oncorhynchusmykiss)</title><source>ScienceDirect Freedom Collection 2022-2024</source><creator>Salem, Mohamed Omar Abdalla ; Taştan, Yiğit ; Bilen, Soner ; Terzi, Ertugrul ; Sönmez, Adem Yavuz</creator><creatorcontrib>Salem, Mohamed Omar Abdalla ; Taştan, Yiğit ; Bilen, Soner ; Terzi, Ertugrul ; Sönmez, Adem Yavuz</creatorcontrib><description><![CDATA[This paper describes the effects of flaxseed (Linum usitatissimum) oil (FSO) as a feed additive on growth performance, oxidative stress, immunity, and disease resistance in rainbow trout (Oncorhynchus mykiss). Eight-hundred-and-forty rainbow trout individuals (mean weight: 25.66 ± 1.33 g) were fed with different doses of FSO (0.5, 1, and 1.5%) ad libitum two times a day for 9 weeks. At the end of the feeding, growth performance was evaluated and the fish were challenged with two different bacteria (Yersinia ruckeri and Aeromonas hydrophila). At the end of the 3rd, 6th, and 9th weeks, blood and tissue samples were taken from 9 fish per treatment to evaluate innate immune response, cytokine gene expression levels, antioxidant enzyme activities and lipid peroxidation levels, and digestive enzyme activities. Determination of haematological parameters and histological examination was also carried out to evaluate the general health status of the fish. Results showed that the final weight and specific growth rate of FSO-supplemented fish increased significantly (p < 0.05). FSO-supplemented fish showed higher resistance to Y. ruckeri than the control group (p < 0.05). However, survival rates of all groups in A. hydrophila challenge test were similar (p > 0.05). Among the investigated innate immune response parameters, the potential killing activity of phagocytes, myeloperoxidase activity, and lysozyme activity increased in the FSO-supplemented groups (p < 0.05). Almost all cytokine gene expression levels in the experimental groups up-regulated especially after 9 weeks of feeding in the head kidney and intestine (p < 0.05). Similarly, superoxide dismutase and catalase activities were found to be significantly higher in the FSO group than in the control (p < 0.05) whereas, the lipid peroxidation levels drastically declined as a result of the FSO supplementation (p < 0.05). These results suggest that FSO can improve growth, enhance immune response, and lower oxidative damage in rainbow trout when supplemented at the rates of 0.5–1.5% for 9 weeks. •Rainbow trout were supplemented with flaxseed (Linum usitatissimum) oil (FSO).•FSO increased innate immune response and provided protection against Yersinia ruckeri.•FSO enhanced growth performance of the fish.•It also increased antioxidant enzyme activities and decreased lipid peroxidation.•1.5% FSO supplementation for 9 weeks can be used in rainbow trout farming.]]></description><identifier>ISSN: 1050-4648</identifier><identifier>EISSN: 1095-9947</identifier><identifier>DOI: 10.1016/j.fsi.2023.108798</identifier><identifier>PMID: 37150237</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Feed additive ; Growth promoter ; Immunostimulant ; Natural product ; Plant oil</subject><ispartof>Fish &amp; shellfish immunology, 2023-07, Vol.138, p.108798-108798, Article 108798</ispartof><rights>2023 Elsevier Ltd</rights><rights>Copyright © 2023 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c353t-c29d480749eb74607ab50b1f1b03c41fcb3abf91ee007f57beebc9087b97b5613</citedby><cites>FETCH-LOGICAL-c353t-c29d480749eb74607ab50b1f1b03c41fcb3abf91ee007f57beebc9087b97b5613</cites><orcidid>0000-0003-2811-6497 ; 0000-0001-9459-8178</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37150237$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Salem, Mohamed Omar Abdalla</creatorcontrib><creatorcontrib>Taştan, Yiğit</creatorcontrib><creatorcontrib>Bilen, Soner</creatorcontrib><creatorcontrib>Terzi, Ertugrul</creatorcontrib><creatorcontrib>Sönmez, Adem Yavuz</creatorcontrib><title>Dietary flaxseed (Linum usitatissimum) oil supplementation affects growth, oxidative stress, immune response, and diseases resistance in rainbow trout (Oncorhynchusmykiss)</title><title>Fish &amp; shellfish immunology</title><addtitle>Fish Shellfish Immunol</addtitle><description><![CDATA[This paper describes the effects of flaxseed (Linum usitatissimum) oil (FSO) as a feed additive on growth performance, oxidative stress, immunity, and disease resistance in rainbow trout (Oncorhynchus mykiss). Eight-hundred-and-forty rainbow trout individuals (mean weight: 25.66 ± 1.33 g) were fed with different doses of FSO (0.5, 1, and 1.5%) ad libitum two times a day for 9 weeks. At the end of the feeding, growth performance was evaluated and the fish were challenged with two different bacteria (Yersinia ruckeri and Aeromonas hydrophila). At the end of the 3rd, 6th, and 9th weeks, blood and tissue samples were taken from 9 fish per treatment to evaluate innate immune response, cytokine gene expression levels, antioxidant enzyme activities and lipid peroxidation levels, and digestive enzyme activities. Determination of haematological parameters and histological examination was also carried out to evaluate the general health status of the fish. Results showed that the final weight and specific growth rate of FSO-supplemented fish increased significantly (p < 0.05). FSO-supplemented fish showed higher resistance to Y. ruckeri than the control group (p < 0.05). However, survival rates of all groups in A. hydrophila challenge test were similar (p > 0.05). Among the investigated innate immune response parameters, the potential killing activity of phagocytes, myeloperoxidase activity, and lysozyme activity increased in the FSO-supplemented groups (p < 0.05). Almost all cytokine gene expression levels in the experimental groups up-regulated especially after 9 weeks of feeding in the head kidney and intestine (p < 0.05). Similarly, superoxide dismutase and catalase activities were found to be significantly higher in the FSO group than in the control (p < 0.05) whereas, the lipid peroxidation levels drastically declined as a result of the FSO supplementation (p < 0.05). These results suggest that FSO can improve growth, enhance immune response, and lower oxidative damage in rainbow trout when supplemented at the rates of 0.5–1.5% for 9 weeks. •Rainbow trout were supplemented with flaxseed (Linum usitatissimum) oil (FSO).•FSO increased innate immune response and provided protection against Yersinia ruckeri.•FSO enhanced growth performance of the fish.•It also increased antioxidant enzyme activities and decreased lipid peroxidation.•1.5% FSO supplementation for 9 weeks can be used in rainbow trout farming.]]></description><subject>Feed additive</subject><subject>Growth promoter</subject><subject>Immunostimulant</subject><subject>Natural product</subject><subject>Plant oil</subject><issn>1050-4648</issn><issn>1095-9947</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9UcuO1DAQjBCIXRY-gAvycVaaDHZeTsQJLU9ppL3A2bKdDuMhtoPb3t35Jn4SR7Nw5NTd7qpSu6ooXjO6Y5R1b4-7Cc2uolWd554P_ZPiktGhLYeh4U_XvqVl0zX9RfEC8Ugp7eqOPi8uas7azOKXxe8PBqIMJzLN8gEBRrLZG5csSWiijAbR2GSviTczwbQsM1hw68I7IqcJdETyI_j7eNgS_2DGvLkDgjEA4pYYa5MDkofFO4QtkW4ko0GQCLg-G4zSaSDGkSCNU_6exOBTJJtbp304nJw-JLSnn_mQ65fFs0nOCK8e61Xx_dPHbzdfyv3t56837_elrts6lroaxqanvBlA8aajXKqWKjYxRWvdsEmrWqppYACU8qnlCkDpIfunBq7ajtVXxeasuwT_KwFGYQ1qmGfpwCcUVc9Yxdq-bjKUnaE6eMQAk1iCsdlPwahYMxJHkTMSa0binFHmvHmUT8rC-I_xN5QMeHcGQP7knYEgUBvINo0mZMPF6M1_5P8AOjunFQ</recordid><startdate>202307</startdate><enddate>202307</enddate><creator>Salem, Mohamed Omar Abdalla</creator><creator>Taştan, Yiğit</creator><creator>Bilen, Soner</creator><creator>Terzi, Ertugrul</creator><creator>Sönmez, Adem Yavuz</creator><general>Elsevier Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2811-6497</orcidid><orcidid>https://orcid.org/0000-0001-9459-8178</orcidid></search><sort><creationdate>202307</creationdate><title>Dietary flaxseed (Linum usitatissimum) oil supplementation affects growth, oxidative stress, immune response, and diseases resistance in rainbow trout (Oncorhynchusmykiss)</title><author>Salem, Mohamed Omar Abdalla ; Taştan, Yiğit ; Bilen, Soner ; Terzi, Ertugrul ; Sönmez, Adem Yavuz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c353t-c29d480749eb74607ab50b1f1b03c41fcb3abf91ee007f57beebc9087b97b5613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Feed additive</topic><topic>Growth promoter</topic><topic>Immunostimulant</topic><topic>Natural product</topic><topic>Plant oil</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Salem, Mohamed Omar Abdalla</creatorcontrib><creatorcontrib>Taştan, Yiğit</creatorcontrib><creatorcontrib>Bilen, Soner</creatorcontrib><creatorcontrib>Terzi, Ertugrul</creatorcontrib><creatorcontrib>Sönmez, Adem Yavuz</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fish &amp; shellfish immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Salem, Mohamed Omar Abdalla</au><au>Taştan, Yiğit</au><au>Bilen, Soner</au><au>Terzi, Ertugrul</au><au>Sönmez, Adem Yavuz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dietary flaxseed (Linum usitatissimum) oil supplementation affects growth, oxidative stress, immune response, and diseases resistance in rainbow trout (Oncorhynchusmykiss)</atitle><jtitle>Fish &amp; shellfish immunology</jtitle><addtitle>Fish Shellfish Immunol</addtitle><date>2023-07</date><risdate>2023</risdate><volume>138</volume><spage>108798</spage><epage>108798</epage><pages>108798-108798</pages><artnum>108798</artnum><issn>1050-4648</issn><eissn>1095-9947</eissn><abstract><![CDATA[This paper describes the effects of flaxseed (Linum usitatissimum) oil (FSO) as a feed additive on growth performance, oxidative stress, immunity, and disease resistance in rainbow trout (Oncorhynchus mykiss). Eight-hundred-and-forty rainbow trout individuals (mean weight: 25.66 ± 1.33 g) were fed with different doses of FSO (0.5, 1, and 1.5%) ad libitum two times a day for 9 weeks. At the end of the feeding, growth performance was evaluated and the fish were challenged with two different bacteria (Yersinia ruckeri and Aeromonas hydrophila). At the end of the 3rd, 6th, and 9th weeks, blood and tissue samples were taken from 9 fish per treatment to evaluate innate immune response, cytokine gene expression levels, antioxidant enzyme activities and lipid peroxidation levels, and digestive enzyme activities. Determination of haematological parameters and histological examination was also carried out to evaluate the general health status of the fish. Results showed that the final weight and specific growth rate of FSO-supplemented fish increased significantly (p < 0.05). FSO-supplemented fish showed higher resistance to Y. ruckeri than the control group (p < 0.05). However, survival rates of all groups in A. hydrophila challenge test were similar (p > 0.05). Among the investigated innate immune response parameters, the potential killing activity of phagocytes, myeloperoxidase activity, and lysozyme activity increased in the FSO-supplemented groups (p < 0.05). Almost all cytokine gene expression levels in the experimental groups up-regulated especially after 9 weeks of feeding in the head kidney and intestine (p < 0.05). Similarly, superoxide dismutase and catalase activities were found to be significantly higher in the FSO group than in the control (p < 0.05) whereas, the lipid peroxidation levels drastically declined as a result of the FSO supplementation (p < 0.05). These results suggest that FSO can improve growth, enhance immune response, and lower oxidative damage in rainbow trout when supplemented at the rates of 0.5–1.5% for 9 weeks. •Rainbow trout were supplemented with flaxseed (Linum usitatissimum) oil (FSO).•FSO increased innate immune response and provided protection against Yersinia ruckeri.•FSO enhanced growth performance of the fish.•It also increased antioxidant enzyme activities and decreased lipid peroxidation.•1.5% FSO supplementation for 9 weeks can be used in rainbow trout farming.]]></abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>37150237</pmid><doi>10.1016/j.fsi.2023.108798</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0003-2811-6497</orcidid><orcidid>https://orcid.org/0000-0001-9459-8178</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 1050-4648
ispartof Fish & shellfish immunology, 2023-07, Vol.138, p.108798-108798, Article 108798
issn 1050-4648
1095-9947
language eng
recordid cdi_proquest_miscellaneous_2811215834
source ScienceDirect Freedom Collection 2022-2024
subjects Feed additive
Growth promoter
Immunostimulant
Natural product
Plant oil
title Dietary flaxseed (Linum usitatissimum) oil supplementation affects growth, oxidative stress, immune response, and diseases resistance in rainbow trout (Oncorhynchusmykiss)
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T02%3A08%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Dietary%20flaxseed%20(Linum%20usitatissimum)%20oil%20supplementation%20affects%20growth,%20oxidative%20stress,%20immune%20response,%20and%20diseases%20resistance%20in%20rainbow%20trout%20(Oncorhynchusmykiss)&rft.jtitle=Fish%20&%20shellfish%20immunology&rft.au=Salem,%20Mohamed%20Omar%20Abdalla&rft.date=2023-07&rft.volume=138&rft.spage=108798&rft.epage=108798&rft.pages=108798-108798&rft.artnum=108798&rft.issn=1050-4648&rft.eissn=1095-9947&rft_id=info:doi/10.1016/j.fsi.2023.108798&rft_dat=%3Cproquest_cross%3E2811215834%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c353t-c29d480749eb74607ab50b1f1b03c41fcb3abf91ee007f57beebc9087b97b5613%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2811215834&rft_id=info:pmid/37150237&rfr_iscdi=true