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Effects of delayed hospitalization on the 3‐year clinical outcomes of patients with or without diabetes who had non‐ST‐segment‐elevation myocardial infarction and underwent new‐generation drug‐eluting stent implantation
Clinical outcomes after non‐ST‐segment‐elevation myocardial infarction (NSTEMI) in patients with (symptom‐to‐door time [SDT] ≥ 24 h) or without (SDT
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| Published in: | Catheterization and cardiovascular interventions 2023-05, Vol.101 (6), p.1014-1027 |
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| container_end_page | 1027 |
| container_issue | 6 |
| container_start_page | 1014 |
| container_title | Catheterization and cardiovascular interventions |
| container_volume | 101 |
| creator | Kim, Yong Hoon Her, Ae‐Young Rha, Seung‐Woon Choi, Cheol Ung Choi, Byoung Geol Kim, Ji Bak Kang, Dong Oh Park, Ji Young Park, Sang‐Ho Jeong, Myung Ho |
| description | Clinical outcomes after non‐ST‐segment‐elevation myocardial infarction (NSTEMI) in patients with (symptom‐to‐door time [SDT] ≥ 24 h) or without (SDT |
| doi_str_mv | 10.1002/ccd.30630 |
| format | article |
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From the Korea Acute Myocardial Infarction Registry‐National Institute of Health, a total of 4517 patients with NSTEMI who underwent new‐generation drug‐eluting stents implantation were recruited and they were classified into the diabetes mellitus (DM) and non‐DM groups. These two groups were subdivided into groups with and without delayed hospitalization. The primary clinical outcome was the occurrence of major adverse cardiac and cerebrovascular events (MACCE), defined as all‐cause death, recurrent myocardial infarction, repeat coronary revascularization, and stroke. The secondary clinical outcome was the occurrence of individual components of MACCE and stent thrombosis. Although after multivariable and propensity score‐adjusted analyses in the DM group, the primary and secondary clinical outcomes between the SDT < 24 h and SDT ≥ 24 h groups were similar; in the non‐DM group, all‐cause (p = 0.003 and p = 0.007, respectively) and cardiac (p = 0.001 and p = 0.008, respectively) death rates were significantly higher in the SDT ≥ 24 h group than in the SDT < 24 h group. Our results suggested that there was no significant difference in prognosis between diabetic patients with and without delayed SDT, but delayed SDT was associated with poor prognosis in nondiabetic patients.</description><identifier>ISSN: 1522-1946</identifier><identifier>EISSN: 1522-726X</identifier><identifier>DOI: 10.1002/ccd.30630</identifier><identifier>PMID: 36923997</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Cerebral infarction ; Clinical outcomes ; Diabetes ; Diabetes mellitus ; Diabetes Mellitus - diagnosis ; Diabetes Mellitus - epidemiology ; Drug-Eluting Stents ; drug‐eluting stent ; Heart ; Heart attacks ; Hospitalization ; Humans ; Implants ; Myocardial infarction ; Myocardial Infarction - etiology ; Myocardial Infarction - therapy ; Non-ST Elevated Myocardial Infarction - diagnostic imaging ; Non-ST Elevated Myocardial Infarction - etiology ; Non-ST Elevated Myocardial Infarction - therapy ; non‐ST‐segment‐elevation myocardial infarction ; Percutaneous Coronary Intervention - adverse effects ; Percutaneous Coronary Intervention - methods ; prehospital delay ; Prognosis ; ST Elevation Myocardial Infarction - diagnostic imaging ; ST Elevation Myocardial Infarction - etiology ; ST Elevation Myocardial Infarction - therapy ; Thrombosis ; Treatment Outcome</subject><ispartof>Catheterization and cardiovascular interventions, 2023-05, Vol.101 (6), p.1014-1027</ispartof><rights>2023 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3530-b910afc9583671e58e3420e3fa9c1589509811f94fb9a0a7581c0bba9a2e25cf3</citedby><cites>FETCH-LOGICAL-c3530-b910afc9583671e58e3420e3fa9c1589509811f94fb9a0a7581c0bba9a2e25cf3</cites><orcidid>0000-0002-5187-8310 ; 0000-0002-9990-6843 ; 0000-0001-6777-3508 ; 0000-0001-7912-0336 ; 0000-0003-2424-810X ; 0000-0002-9669-3598</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36923997$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Yong Hoon</creatorcontrib><creatorcontrib>Her, Ae‐Young</creatorcontrib><creatorcontrib>Rha, Seung‐Woon</creatorcontrib><creatorcontrib>Choi, Cheol Ung</creatorcontrib><creatorcontrib>Choi, Byoung Geol</creatorcontrib><creatorcontrib>Kim, Ji Bak</creatorcontrib><creatorcontrib>Kang, Dong Oh</creatorcontrib><creatorcontrib>Park, Ji Young</creatorcontrib><creatorcontrib>Park, Sang‐Ho</creatorcontrib><creatorcontrib>Jeong, Myung Ho</creatorcontrib><title>Effects of delayed hospitalization on the 3‐year clinical outcomes of patients with or without diabetes who had non‐ST‐segment‐elevation myocardial infarction and underwent new‐generation drug‐eluting stent implantation</title><title>Catheterization and cardiovascular interventions</title><addtitle>Catheter Cardiovasc Interv</addtitle><description>Clinical outcomes after non‐ST‐segment‐elevation myocardial infarction (NSTEMI) in patients with (symptom‐to‐door time [SDT] ≥ 24 h) or without (SDT < 24 h) delayed hospitalization among patients with or without diabetes were compared. From the Korea Acute Myocardial Infarction Registry‐National Institute of Health, a total of 4517 patients with NSTEMI who underwent new‐generation drug‐eluting stents implantation were recruited and they were classified into the diabetes mellitus (DM) and non‐DM groups. These two groups were subdivided into groups with and without delayed hospitalization. The primary clinical outcome was the occurrence of major adverse cardiac and cerebrovascular events (MACCE), defined as all‐cause death, recurrent myocardial infarction, repeat coronary revascularization, and stroke. The secondary clinical outcome was the occurrence of individual components of MACCE and stent thrombosis. Although after multivariable and propensity score‐adjusted analyses in the DM group, the primary and secondary clinical outcomes between the SDT < 24 h and SDT ≥ 24 h groups were similar; in the non‐DM group, all‐cause (p = 0.003 and p = 0.007, respectively) and cardiac (p = 0.001 and p = 0.008, respectively) death rates were significantly higher in the SDT ≥ 24 h group than in the SDT < 24 h group. Our results suggested that there was no significant difference in prognosis between diabetic patients with and without delayed SDT, but delayed SDT was associated with poor prognosis in nondiabetic patients.</description><subject>Cerebral infarction</subject><subject>Clinical outcomes</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes Mellitus - diagnosis</subject><subject>Diabetes Mellitus - epidemiology</subject><subject>Drug-Eluting Stents</subject><subject>drug‐eluting stent</subject><subject>Heart</subject><subject>Heart attacks</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Implants</subject><subject>Myocardial infarction</subject><subject>Myocardial Infarction - etiology</subject><subject>Myocardial Infarction - therapy</subject><subject>Non-ST Elevated Myocardial Infarction - diagnostic imaging</subject><subject>Non-ST Elevated Myocardial Infarction - etiology</subject><subject>Non-ST Elevated Myocardial Infarction - therapy</subject><subject>non‐ST‐segment‐elevation myocardial infarction</subject><subject>Percutaneous Coronary Intervention - adverse effects</subject><subject>Percutaneous Coronary Intervention - methods</subject><subject>prehospital delay</subject><subject>Prognosis</subject><subject>ST Elevation Myocardial Infarction - diagnostic imaging</subject><subject>ST Elevation Myocardial Infarction - etiology</subject><subject>ST Elevation Myocardial Infarction - therapy</subject><subject>Thrombosis</subject><subject>Treatment Outcome</subject><issn>1522-1946</issn><issn>1522-726X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp1kc2K1TAUx4sozji68AUk4MZZ3Jl89CtLuc6oMODCEdyVND25zZAmNUktdeUj-IxufA0z7dWFIIScQ_j9fzlwsuw5wRcEY3opZXfBcMnwg-yUFJTuKlp-fnjsCc_Lk-xJCHcYY15S_jg7YSWnjPPqNPt1pRTIGJBTqAMjFuhQ78KoozD6m4jaWZRO7AGxn99_LCA8kkZbLYVBborSDbCGx8SCTaJZxx45v9YEoE6LFmKC5t6hXnTIOptMH2_TFeAwpFDqwMDX7bdhcVL4lDJIWyW8XF-F7dBkO_Bz4pGFOWUOYMFvoc5Ph9UyRW0PKMR7Sg-jETauxNPskRImwLNjPcs-XV_d7t_tbj68fb9_fbOTrGB413KChZK8qFlZEShqYDnFwJTgkhQ1LzCvCVE8Vy0XWFRFTSRuW8EFBVpIxc6yV5t39O7LBCE2gw4STBoE3BQamuKc8RpXCX35D3rnJm_TdCuVc0LzOlHnGyW9C8GDakavB-GXhuDmfvtN2n6zbj-xL47GqR2g-0v-WXcCLjdg1gaW_5ua_f7NpvwNA9rFMQ</recordid><startdate>20230501</startdate><enddate>20230501</enddate><creator>Kim, Yong Hoon</creator><creator>Her, Ae‐Young</creator><creator>Rha, Seung‐Woon</creator><creator>Choi, Cheol Ung</creator><creator>Choi, Byoung Geol</creator><creator>Kim, Ji Bak</creator><creator>Kang, Dong Oh</creator><creator>Park, Ji Young</creator><creator>Park, Sang‐Ho</creator><creator>Jeong, Myung Ho</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5187-8310</orcidid><orcidid>https://orcid.org/0000-0002-9990-6843</orcidid><orcidid>https://orcid.org/0000-0001-6777-3508</orcidid><orcidid>https://orcid.org/0000-0001-7912-0336</orcidid><orcidid>https://orcid.org/0000-0003-2424-810X</orcidid><orcidid>https://orcid.org/0000-0002-9669-3598</orcidid></search><sort><creationdate>20230501</creationdate><title>Effects of delayed hospitalization on the 3‐year clinical outcomes of patients with or without diabetes who had non‐ST‐segment‐elevation myocardial infarction and underwent new‐generation drug‐eluting stent implantation</title><author>Kim, Yong Hoon ; Her, Ae‐Young ; Rha, Seung‐Woon ; Choi, Cheol Ung ; Choi, Byoung Geol ; Kim, Ji Bak ; Kang, Dong Oh ; Park, Ji Young ; Park, Sang‐Ho ; Jeong, Myung Ho</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3530-b910afc9583671e58e3420e3fa9c1589509811f94fb9a0a7581c0bba9a2e25cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Cerebral infarction</topic><topic>Clinical outcomes</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetes Mellitus - diagnosis</topic><topic>Diabetes Mellitus - epidemiology</topic><topic>Drug-Eluting Stents</topic><topic>drug‐eluting stent</topic><topic>Heart</topic><topic>Heart attacks</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Implants</topic><topic>Myocardial infarction</topic><topic>Myocardial Infarction - etiology</topic><topic>Myocardial Infarction - therapy</topic><topic>Non-ST Elevated Myocardial Infarction - diagnostic imaging</topic><topic>Non-ST Elevated Myocardial Infarction - etiology</topic><topic>Non-ST Elevated Myocardial Infarction - therapy</topic><topic>non‐ST‐segment‐elevation myocardial infarction</topic><topic>Percutaneous Coronary Intervention - adverse effects</topic><topic>Percutaneous Coronary Intervention - methods</topic><topic>prehospital delay</topic><topic>Prognosis</topic><topic>ST Elevation Myocardial Infarction - diagnostic imaging</topic><topic>ST Elevation Myocardial Infarction - etiology</topic><topic>ST Elevation Myocardial Infarction - therapy</topic><topic>Thrombosis</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Yong Hoon</creatorcontrib><creatorcontrib>Her, Ae‐Young</creatorcontrib><creatorcontrib>Rha, Seung‐Woon</creatorcontrib><creatorcontrib>Choi, Cheol Ung</creatorcontrib><creatorcontrib>Choi, Byoung Geol</creatorcontrib><creatorcontrib>Kim, Ji Bak</creatorcontrib><creatorcontrib>Kang, Dong Oh</creatorcontrib><creatorcontrib>Park, Ji Young</creatorcontrib><creatorcontrib>Park, Sang‐Ho</creatorcontrib><creatorcontrib>Jeong, Myung Ho</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Catheterization and cardiovascular interventions</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Yong Hoon</au><au>Her, Ae‐Young</au><au>Rha, Seung‐Woon</au><au>Choi, Cheol Ung</au><au>Choi, Byoung Geol</au><au>Kim, Ji Bak</au><au>Kang, Dong Oh</au><au>Park, Ji Young</au><au>Park, Sang‐Ho</au><au>Jeong, Myung Ho</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of delayed hospitalization on the 3‐year clinical outcomes of patients with or without diabetes who had non‐ST‐segment‐elevation myocardial infarction and underwent new‐generation drug‐eluting stent implantation</atitle><jtitle>Catheterization and cardiovascular interventions</jtitle><addtitle>Catheter Cardiovasc Interv</addtitle><date>2023-05-01</date><risdate>2023</risdate><volume>101</volume><issue>6</issue><spage>1014</spage><epage>1027</epage><pages>1014-1027</pages><issn>1522-1946</issn><eissn>1522-726X</eissn><abstract>Clinical outcomes after non‐ST‐segment‐elevation myocardial infarction (NSTEMI) in patients with (symptom‐to‐door time [SDT] ≥ 24 h) or without (SDT < 24 h) delayed hospitalization among patients with or without diabetes were compared. From the Korea Acute Myocardial Infarction Registry‐National Institute of Health, a total of 4517 patients with NSTEMI who underwent new‐generation drug‐eluting stents implantation were recruited and they were classified into the diabetes mellitus (DM) and non‐DM groups. These two groups were subdivided into groups with and without delayed hospitalization. The primary clinical outcome was the occurrence of major adverse cardiac and cerebrovascular events (MACCE), defined as all‐cause death, recurrent myocardial infarction, repeat coronary revascularization, and stroke. The secondary clinical outcome was the occurrence of individual components of MACCE and stent thrombosis. Although after multivariable and propensity score‐adjusted analyses in the DM group, the primary and secondary clinical outcomes between the SDT < 24 h and SDT ≥ 24 h groups were similar; in the non‐DM group, all‐cause (p = 0.003 and p = 0.007, respectively) and cardiac (p = 0.001 and p = 0.008, respectively) death rates were significantly higher in the SDT ≥ 24 h group than in the SDT < 24 h group. Our results suggested that there was no significant difference in prognosis between diabetic patients with and without delayed SDT, but delayed SDT was associated with poor prognosis in nondiabetic patients.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>36923997</pmid><doi>10.1002/ccd.30630</doi><tpages>14</tpages><orcidid>https://orcid.org/0000-0002-5187-8310</orcidid><orcidid>https://orcid.org/0000-0002-9990-6843</orcidid><orcidid>https://orcid.org/0000-0001-6777-3508</orcidid><orcidid>https://orcid.org/0000-0001-7912-0336</orcidid><orcidid>https://orcid.org/0000-0003-2424-810X</orcidid><orcidid>https://orcid.org/0000-0002-9669-3598</orcidid></addata></record> |
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| ispartof | Catheterization and cardiovascular interventions, 2023-05, Vol.101 (6), p.1014-1027 |
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| source | Wiley-Blackwell Read & Publish Collection |
| subjects | Cerebral infarction Clinical outcomes Diabetes Diabetes mellitus Diabetes Mellitus - diagnosis Diabetes Mellitus - epidemiology Drug-Eluting Stents drug‐eluting stent Heart Heart attacks Hospitalization Humans Implants Myocardial infarction Myocardial Infarction - etiology Myocardial Infarction - therapy Non-ST Elevated Myocardial Infarction - diagnostic imaging Non-ST Elevated Myocardial Infarction - etiology Non-ST Elevated Myocardial Infarction - therapy non‐ST‐segment‐elevation myocardial infarction Percutaneous Coronary Intervention - adverse effects Percutaneous Coronary Intervention - methods prehospital delay Prognosis ST Elevation Myocardial Infarction - diagnostic imaging ST Elevation Myocardial Infarction - etiology ST Elevation Myocardial Infarction - therapy Thrombosis Treatment Outcome |
| title | Effects of delayed hospitalization on the 3‐year clinical outcomes of patients with or without diabetes who had non‐ST‐segment‐elevation myocardial infarction and underwent new‐generation drug‐eluting stent implantation |
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