Deposition of phospholipid layers on SiO2 surface modified by alkyl-SAM islands

Formation of the supported planar bilayer of dipalmitoylphosphatidylcholine (DPPC) on SiO2 surfaces modified with the self-assembled monolayer (SAM) of octadecyltrichlorosilane (OTS) has been investigated by atomic force microscopy (AFM). DPPC was deposited by the fusion of vesicles on SiO2 surfaces...

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Bibliographic Details
Published in:Applied surface science 2004-11, Vol.238 (1-4), p.218-222
Main Authors: Tero, R., Takizawa, M., Li, Y.J., Yamazaki, M., Urisu, T.
Format: Article
Language:English
Subjects:
Atomic force microscopy
Bilayer
Biological and medical sciences
Cell membranes. Ionic channels. Membrane pores
Cell structures and functions
Cross-disciplinary physics: materials science
rheology
Exact sciences and technology
Fundamental and applied biological sciences. Psychology
Fusion
Materials science
Membranes, bilayers, and vesicles
Methods of nanofabrication
Molecular and cellular biology
Phospholipid
Physics
Self-assembly
Silicon oxides
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Summary:Formation of the supported planar bilayer of dipalmitoylphosphatidylcholine (DPPC) on SiO2 surfaces modified with the self-assembled monolayer (SAM) of octadecyltrichlorosilane (OTS) has been investigated by atomic force microscopy (AFM). DPPC was deposited by the fusion of vesicles on SiO2 surfaces with OTS-SAM islands of different sizes and densities. The DPPC bilayer membrane formed self-organizingly on the SiO2 surface with small and sparse OTS islands, while did not when the OTS islands were larger and denser. The relative size between the vesicles and the SiO2 regions is the critical factor for the formation of the DPPC bilayer membrane.
ISSN:0169-4332
1873-5584
DOI:10.1016/j.apsusc.2004.05.203