Painful ulcers on the penis

Multiple painful ulcers on the penis Table 1 shows the results of relevant laboratory tests.Table 1 Laboratory test results Test Result Dark field microscopy Negative Rapid plasma reagin Negative Treponema pallidum particle agglutination Positive HIV antibodies Negative HSV-1 PCR test of ulcer sampl...

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Bibliographic Details
Published in:BMJ (Online) 2023-05, Vol.381, p.e071601-e071601
Main Authors: He, Yong, Jiang, Ming-jun, Xiong, Jing-shu, Wang, Hong-sheng
Format: Article
Language:English
Subjects:
Agglutination
Antibodies
Behcet's syndrome
Chancroid
Disease transmission
Endgames
Fever
Herpes simplex
Herpes viruses
HIV
Human immunodeficiency virus
Humans
Infections
Laboratories
Male
Mpox
Pain - etiology
Patients
Pelvis
Penis
Polymerase chain reaction
Reagin
Serology
Sexually transmitted diseases
Skin eruptions
STD
Syphilis
Ulcer
Ulcers
Viruses
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Summary:Multiple painful ulcers on the penis Table 1 shows the results of relevant laboratory tests.Table 1 Laboratory test results Test Result Dark field microscopy Negative Rapid plasma reagin Negative Treponema pallidum particle agglutination Positive HIV antibodies Negative HSV-1 PCR test of ulcer sample Negative Serum HSV-1 antibodies Negative HSV-2 PCR test of ulcer sample Positive Serum HSV-2 antibodies Positive HSV-1=herpes simplex virus type 1; HSV-2=herpes simplex virus type 2; PCR=polymerase chain reaction. Differential diagnoses include genital herpes simplex virus (HSV) infection, syphilis, HIV infection, chancroid, mpox, fixed drug eruptions, and Behcet’s syndrome. Genital herpes is mostly caused by HSV type 2; HSV type 1 mainly causes oral infections.5 Transmission occurs by skin-to-skin contact, usually during sexual activity.6 Typically, genital herpes is characterised by groups of blisters on an erythematous base.
ISSN:1756-1833
1756-1833
DOI:10.1136/bmj-2022-071601