Dynamics of atlantoaxial rotation related to age and sex: a cross-sectional study of 308 subjects

• Published in: The spine journal 2023-09, Vol.23 (9), p.1276-1286
• Main Authors: Lodin, Jan, Terč, Jan, Cihlář, Filip, Sameš, Martin, Cihlář, Jiří, Vachata, Petr
• Format: Article
• Language: English
• Subjects: Age; Atlantoaxial fusion; Biomechanics; Functional exam; Joint; Range of motion; Rotation; Sex
• ISSN: 1529-9430; 1878-1632; 1878-1632
• DOI: 10.1016/j.spinee.2023.05.008

•Atlantoaxial rotation and cervical spine rotation significantly decrease with age.•Females have higher values of cervical spine rotation compared to males.•Atlantoaxial and cervical spine rotation have different sex-based dynamics. [Display omitted] Physiological ranges and dynamic changes of atlantoaxial rotation (ROTC1/2), total cervical spine rotation (ROTCs) and the percentage of ROTC1/2 from ROTCs (ROTCperc) for different age groups have not yet been investigated in a sufficiently sized cohort. Furthermore, it is not clear whether demographic variables such a sex, smoking status or diabetes affect ROTC1/2, ROTCs and ROTCperc. Obtain physiological ranges of ROTC1/2, ROTCs and ROTCperc for different age groups and determine their age-based dynamics. Investigate whether ROTC1/2, ROTCs and ROTCperc are affected by sex, smoking status or diabetes Observational cross-sectional study Patients undergoing elective CT examinations of the head and neck region between August 2020 and January 2022. Ranges of motion of ROTC1/2, ROTCs and ROTCperc in degrees A total of 308 subjects underwent dynamic rotational CT examinations of the upper cervical spine. Patients were divided into three age categories A1 (27-49 years), A2 (50-69 years) and A3 (≥70 years). Category A3 was further divided into B1 (70-79 years) and B2 (≥80 years). Values of ROTC1/2, ROTCs and ROTCperc were compared between all age groups, males and females, smokers and nonsmokers, diabetics a nondiabetics. Dynamics of ROTC1/2, ROTCs related to age and sex were visualized using scatterplot and trendline models. ROTC1/2 significantly decreased from group A1 (64.4°) to B2 (46.7°) as did ROTCs from A1 (131.2°) to B2 (97.6°). No significant differences of ROTperc were found between groups A1-B2 with values oscillating between 49% and 51%. Smoking and diabetes did not significantly affect ROTC1/2, ROTCs and ROTCperc, females had significantly higher ROTCs than males. Males and females demonstrated a different dynamic of ROTC1/2 and ROTCs demonstrated by out scatterplot and trendline models. Both ROTC1/2 and ROTCs significantly decrease with age, whereas ROTCperc remains stable. Females demonstrated higher ROTCs and their decrease of ROTC1/2 and ROTCs occurred in higher age groups compared to males. The functional repercussions atlantoaxial fusion are variable based on patient age and sex and should be taken into account prior to surgery.