Pediatric Heart Transplant Rejection After COVID-19 Infection

•A patient who underwent a heart transplant had COVID-19 followed by rejection and graft dysfunction.•This study highlights the potential association between rejection and COVID-19 infection. Infections have been associated with rejection episodes in solid organ transplant recipients. We report an a...

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Bibliographic Details
Published in:Transplantation proceedings 2023-10, Vol.55 (8), p.1858-1861
Main Authors: Shea, Erin V., Sinicropi, Natalie L., Cusick, Matthew F., Rabah, Raja, Lim, Heang M., Schumacher, Kurt R., McCormick, Amanda D., Peng, David M.
Format: Article
Language:English
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Summary:•A patient who underwent a heart transplant had COVID-19 followed by rejection and graft dysfunction.•This study highlights the potential association between rejection and COVID-19 infection. Infections have been associated with rejection episodes in solid organ transplant recipients. We report an association between COVID-19 infection and heart transplant (HT) rejection. The patient was 14 years old and 6.5 years post-HT. He developed symptoms of rejection within 2 weeks of COVID exposure and presumed infection. In this case, COVID-19 infection closely preceded significant rejection and graft dysfunction. Further study is needed to establish a correlation between COVID-19 infection and rejection in HT patients.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2023.04.021