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Five-year outcomes of tricuspid valve repair versus replacement; a propensity score-matched analysis

Background Tricuspid valve repair (TVr) is the recommended approach for managing tricuspid regurgitation; however, there is a concern about the long-term durability of the repair. Therefore, this study aimed to compare the long-term outcomes of TVr versus tricuspid valve replacement (TVR) in a match...

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Published in:Asian cardiovascular & thoracic annals 2023-06, Vol.31 (5), p.413-420
Main Authors: Alghamdi, Rawan, Alaloola, Alhnouf A, Aldaghar, Abdulelah S, Alfonso, Juan, Ismail, Huda, Adam, Adam I, Pragliola, Claudio, Albabtain, Monirah A, Arafat, Amr A
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container_end_page 420
container_issue 5
container_start_page 413
container_title Asian cardiovascular & thoracic annals
container_volume 31
creator Alghamdi, Rawan
Alaloola, Alhnouf A
Aldaghar, Abdulelah S
Alfonso, Juan
Ismail, Huda
Adam, Adam I
Pragliola, Claudio
Albabtain, Monirah A
Arafat, Amr A
description Background Tricuspid valve repair (TVr) is the recommended approach for managing tricuspid regurgitation; however, there is a concern about the long-term durability of the repair. Therefore, this study aimed to compare the long-term outcomes of TVr versus tricuspid valve replacement (TVR) in a matched cohort of patients. Methods This study included 1161 patients who underwent tricuspid valve (TV) surgery from 2009 to 2020. Patients were grouped according to the procedure into two groups: patients who underwent TVr (n = 1020) and patients who underwent TVR (n = 159). The propensity score identified 135 matched pairs. Results Renal replacement therapy and bleeding were significantly higher in the TVR group compared to the TVr group both before and after matching. Thirty-day mortality occurred in 38 (3.79%) patients in TVr group versus 3 (1.89%) in the TVR group (P ≤ 0.001) but was not significant after matching. After matching, TV reintervention (hazard ratio (HR): 21.44 (95% CI: 2.17–211.95); P  =  0.009) and heart failure rehospitalization (HR: 1.89 (95% CI: 1.13–3.16); P  =  0.015) were significantly higher in the TVR group. There was no difference in mortality in the matched cohort (HR: 1.63 (95% CI: 0.72–3.70); P  =  0.25). Conclusions TVr was associated with lower renal impairment, reintervention, and heart failure rehospitalization than replacement. TVr remains the preferred approach whenever feasible.
doi_str_mv 10.1177/02184923231176508
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Therefore, this study aimed to compare the long-term outcomes of TVr versus tricuspid valve replacement (TVR) in a matched cohort of patients. Methods This study included 1161 patients who underwent tricuspid valve (TV) surgery from 2009 to 2020. Patients were grouped according to the procedure into two groups: patients who underwent TVr (n = 1020) and patients who underwent TVR (n = 159). The propensity score identified 135 matched pairs. Results Renal replacement therapy and bleeding were significantly higher in the TVR group compared to the TVr group both before and after matching. Thirty-day mortality occurred in 38 (3.79%) patients in TVr group versus 3 (1.89%) in the TVR group (P ≤ 0.001) but was not significant after matching. After matching, TV reintervention (hazard ratio (HR): 21.44 (95% CI: 2.17–211.95); P  =  0.009) and heart failure rehospitalization (HR: 1.89 (95% CI: 1.13–3.16); P  =  0.015) were significantly higher in the TVR group. There was no difference in mortality in the matched cohort (HR: 1.63 (95% CI: 0.72–3.70); P  =  0.25). Conclusions TVr was associated with lower renal impairment, reintervention, and heart failure rehospitalization than replacement. TVr remains the preferred approach whenever feasible.</description><identifier>ISSN: 0218-4923</identifier><identifier>EISSN: 1816-5370</identifier><identifier>DOI: 10.1177/02184923231176508</identifier><identifier>PMID: 37192641</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><ispartof>Asian cardiovascular &amp; thoracic annals, 2023-06, Vol.31 (5), p.413-420</ispartof><rights>The Author(s) 2023</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c292t-edddf61fa0a2084fd1476d94d94a9ea56927edb19195b4e2e391b28bb314886a3</cites><orcidid>0000-0003-0951-7287 ; 0000-0001-5141-5159</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924,79235</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37192641$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alghamdi, Rawan</creatorcontrib><creatorcontrib>Alaloola, Alhnouf A</creatorcontrib><creatorcontrib>Aldaghar, Abdulelah S</creatorcontrib><creatorcontrib>Alfonso, Juan</creatorcontrib><creatorcontrib>Ismail, Huda</creatorcontrib><creatorcontrib>Adam, Adam I</creatorcontrib><creatorcontrib>Pragliola, Claudio</creatorcontrib><creatorcontrib>Albabtain, Monirah A</creatorcontrib><creatorcontrib>Arafat, Amr A</creatorcontrib><title>Five-year outcomes of tricuspid valve repair versus replacement; a propensity score-matched analysis</title><title>Asian cardiovascular &amp; thoracic annals</title><addtitle>Asian Cardiovascular and Thoracic Annals</addtitle><description>Background Tricuspid valve repair (TVr) is the recommended approach for managing tricuspid regurgitation; however, there is a concern about the long-term durability of the repair. Therefore, this study aimed to compare the long-term outcomes of TVr versus tricuspid valve replacement (TVR) in a matched cohort of patients. Methods This study included 1161 patients who underwent tricuspid valve (TV) surgery from 2009 to 2020. Patients were grouped according to the procedure into two groups: patients who underwent TVr (n = 1020) and patients who underwent TVR (n = 159). The propensity score identified 135 matched pairs. Results Renal replacement therapy and bleeding were significantly higher in the TVR group compared to the TVr group both before and after matching. Thirty-day mortality occurred in 38 (3.79%) patients in TVr group versus 3 (1.89%) in the TVR group (P ≤ 0.001) but was not significant after matching. After matching, TV reintervention (hazard ratio (HR): 21.44 (95% CI: 2.17–211.95); P  =  0.009) and heart failure rehospitalization (HR: 1.89 (95% CI: 1.13–3.16); P  =  0.015) were significantly higher in the TVR group. There was no difference in mortality in the matched cohort (HR: 1.63 (95% CI: 0.72–3.70); P  =  0.25). Conclusions TVr was associated with lower renal impairment, reintervention, and heart failure rehospitalization than replacement. 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Therefore, this study aimed to compare the long-term outcomes of TVr versus tricuspid valve replacement (TVR) in a matched cohort of patients. Methods This study included 1161 patients who underwent tricuspid valve (TV) surgery from 2009 to 2020. Patients were grouped according to the procedure into two groups: patients who underwent TVr (n = 1020) and patients who underwent TVR (n = 159). The propensity score identified 135 matched pairs. Results Renal replacement therapy and bleeding were significantly higher in the TVR group compared to the TVr group both before and after matching. Thirty-day mortality occurred in 38 (3.79%) patients in TVr group versus 3 (1.89%) in the TVR group (P ≤ 0.001) but was not significant after matching. After matching, TV reintervention (hazard ratio (HR): 21.44 (95% CI: 2.17–211.95); P  =  0.009) and heart failure rehospitalization (HR: 1.89 (95% CI: 1.13–3.16); P  =  0.015) were significantly higher in the TVR group. There was no difference in mortality in the matched cohort (HR: 1.63 (95% CI: 0.72–3.70); P  =  0.25). Conclusions TVr was associated with lower renal impairment, reintervention, and heart failure rehospitalization than replacement. TVr remains the preferred approach whenever feasible.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>37192641</pmid><doi>10.1177/02184923231176508</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-0951-7287</orcidid><orcidid>https://orcid.org/0000-0001-5141-5159</orcidid></addata></record>
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title Five-year outcomes of tricuspid valve repair versus replacement; a propensity score-matched analysis
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