Research progress on the hematopoietic microenvironment in aplastic anemia

Aplastic anemia (AA) is a disease of bone marrow hematopoietic failure, and the main clinical manifestation is pancytopenia. Its pathogenesis is still unclear. In recent years, more research has been done on its immune abnormalities to explain its pathogenesis and less on the hematopoietic microenvi...

Full description

Saved in:
Bibliographic Details
Published in:European journal of haematology 2023-08, Vol.111 (2), p.172-180
Main Authors: Li, Hangchao, Zhou, Chenjie, Shen, Yingying, Xu, Min, Wu, Dijiong, Ye, Baodong
Format: Article
Language:English
Subjects:
Anemia
Aplastic anemia
hematopoietic microenvironment
Microenvironments
Pancytopenia
Pathogenesis
research progress
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aplastic anemia (AA) is a disease of bone marrow hematopoietic failure, and the main clinical manifestation is pancytopenia. Its pathogenesis is still unclear. In recent years, more research has been done on its immune abnormalities to explain its pathogenesis and less on the hematopoietic microenvironment, but there are still some advances. This article summarizes the research on the hematopoietic microenvironment of AA in recent years to provide new ideas for the clinical treatment of AA.
ISSN:0902-4441
1600-0609
DOI:10.1111/ejh.13991