Mpox virus Clade IIb detection in the air

Mpox is a viral zoonotic disease endemic in Central and West Africa that is caused by the Mpox virus, which belongs to the Orthopoxvirus genus and Poxviridae family. The clinical manifestations of mpox infection are milder than those of smallpox, and the incubation time of mpox varies from 5 to 21 d...

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Bibliographic Details
Published in:Journal of medical virology 2023-05, Vol.95 (5), p.e28775-n/a
Main Author: Saied, AbdulRahman A.
Format: Article
Language:English
Subjects:
Africa
Africa, Central - epidemiology
Africa, Western - epidemiology
air detection
Air Microbiology
Clade I
Clade IIb
DNA viruses
Epidemiology
Genetic analysis
Health care facilities
Humans
Immunocompromised hosts
infection‐competent virus
Monkeypox virus - genetics
Monkeypox virus - isolation & purification
Mpox
Mpox (monkeypox) - diagnosis
Mpox (monkeypox) - epidemiology
Mpox virus
Orthopoxvirus
Outbreaks
Patients
resurgence
Smallpox
transmission
Virology
Viruses
Zoonoses
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Summary:Mpox is a viral zoonotic disease endemic in Central and West Africa that is caused by the Mpox virus, which belongs to the Orthopoxvirus genus and Poxviridae family. The clinical manifestations of mpox infection are milder than those of smallpox, and the incubation time of mpox varies from 5 to 21 days. Since May 2022, the mpox outbreak (formerly known as monkeypox) has suddenly and unexpectedly spread in non‐endemic countries, suggesting that there may have been some undetected transmissions. Based on molecular analysis, there are two major genetic clades that represent the mpox virus: Clade I (formerly the Congo Basin clade OR the Central African clade) and Clade II (formerly the West African clade). It is believed that people who are asymptomatic or paucisymptomatic may spread the mpox virus. Infectious viruses cannot be distinguished by PCR testing; therefore, virus culture should be carried out. Recent evidence regarding the detection of the mpox virus (Clade IIb) in air samples collected from the patient's environment during the 2022 mpox outbreak was reviewed. Further studies are needed to evaluate the extent to which the presence of mpox virus DNA in the air could affect immunocompromised patients in healthcare facilities, and further epidemiological studies are crucial, especially in Africa.
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.28775