A Biocompatible Bottom-Up Route for the Preparation of Hierarchical Biohybrid Materials

Ice‐segregation‐induced self‐ assembly is a versatile and biocompatible process that facilitates the preparation of hierarchical biohybrid materials exhibiting a very sophisticated structure with up to six levels of space organization: the ternary structure of esterase, the PVA domains surrounding e...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2006-05, Vol.18 (9), p.1137-1140
Main Authors: Gutiérrez, M. C., Jobbágy, M., Rapún, N., Ferrer, M. L., del Monte, F.
Format: Article
Language:English
Subjects:
Biocompatible materials
Biosensors
Encapsulation
Enzymes
Hybrid materials
Macroporous materials
Poly(vinyl alcohol)
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Summary:Ice‐segregation‐induced self‐ assembly is a versatile and biocompatible process that facilitates the preparation of hierarchical biohybrid materials exhibiting a very sophisticated structure with up to six levels of space organization: the ternary structure of esterase, the PVA domains surrounding esterase, the silica cages entrapping the PVA domains, and the macroporous structure resulting from ice segregation (see figure). The resulting materials are attractive for biomedical and sensor applications.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200502550