Assessment of the mechanism of mitral valve prolapse in children: An echocardiography study

Background The high complexity of mitral valve anatomy and function in mitral valve prolapse (MVP) is not yet fully understood. Objective The purpose of this study was to analyze each part of the mitral valve apparatus in children to determine its impact on the presence of MVP and to assess the inte...

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Bibliographic Details
Published in:Echocardiography (Mount Kisco, N.Y.) N.Y.), 2023-07, Vol.40 (7), p.664-669
Main Authors: Sabry, Ayman F., Reller, Mark D., Evers, Patrick D., Madriago, Erin J.
Format: Article
Language:English
Subjects:
mitral leaflets
mitral regurgitation
papillary muscles
pediatric mitral valve prolapse
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Summary:Background The high complexity of mitral valve anatomy and function in mitral valve prolapse (MVP) is not yet fully understood. Objective The purpose of this study was to analyze each part of the mitral valve apparatus in children to determine its impact on the presence of MVP and to assess the interaction between the coaptation length (CL) and mitral regurgitation severity. Methods We prospectively analyzed transthoracic echocardiograms of 60 patients with MVP (mean age 9.8 ± 3.1 years). We compared these patients with 60 control patients without disease. We determined length of leaflets, chordal length, tenting area, coaptation CL, the intrapapillary muscle distance (IPMD) and relation between CL and severity of mitral regurgitation (MR). Results For patients with MVP, the posterior mitral leaflet (PML) was significantly enlarged 13.9 ± 4.1 mm versus 10.7 ± 3.5 mm (p 
ISSN:0742-2822
1540-8175
DOI:10.1111/echo.15631