Impact of ileostomy in the adjuvant treatment and outcome of colon cancer

Background After tumor resection, a preventive diverting loop ileostomy creation is a routine surgical procedure to prevent anastomotic leakage and infections and to preclude secondary surgeries. Despite its benefits, several studies have proposed potential complications that extend the disease cour...

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Published in:International journal of colorectal disease 2023-06, Vol.38 (1), p.158-158, Article 158
Main Authors: Calderillo-Ruíz, Germán, López-Basave, Horacio Noé, Muñoz-Montaño, Wendy Rossemary, Díaz-Romero, María Consuelo, Carbajal-López, Berenice, Castillo-Morales, Carolina, Pérez-Yépez, Eloy Andrés, Albarran-García, Alejandra
Format: Article
Language:English
Subjects:
Adjuvant treatment
Analysis
Cancer
Care and treatment
Colon cancer
Complications and side effects
Diarrhea
Gastroenterology
Hepatology
Infection
Internal Medicine
Medicine
Medicine & Public Health
Oncology, Experimental
Patient compliance
Proctology
Surgery
Type 2 diabetes
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Summary:Background After tumor resection, a preventive diverting loop ileostomy creation is a routine surgical procedure to prevent anastomotic leakage and infections and to preclude secondary surgeries. Despite its benefits, several studies have proposed potential complications that extend the disease course by impairing the feasibility of adjuvant chemotherapy and adherence. Purpose The aim of this study was to evaluate the impact of ileostomy complications on the adherence to adjuvant treatment and overall survival (OS) of colon cancer (CC) patients. Methods Retrospective, observational study. Patients diagnosed with colon adenocarcinoma were treated between January 2010 and December 2020 at the National Cancer Institute in Mexico. Statistical analysis χ 2 and t -test, Kaplan–Meier, log-rank, and Cox regression. Statistical significance differences were assessed when p was bilaterally 
ISSN:1432-1262
0179-1958
1432-1262
DOI:10.1007/s00384-023-04421-w