Pseudoresistance to permethrin in scabies

Reports of permethrin resistance of Sarcoptes scabiei var. hominis are emerging. We propose that this may be pseudoresistance. The resistance is due to inadequate counselling by physicians, incorrect treatment (insufficient quantity of permethrin; too short length of treatment), and poor adherence a...

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Bibliographic Details
Published in:Journal of infection in developing countries 2023-05, Vol.17 (5), p.713-715
Main Authors: Veraldi, Stefano, Schianchi, Rossana, Silvio, Martina, Aromolo, Italo Francesco
Format: Article
Language:English
Subjects:
Animals
Humans
Insecticides - pharmacology
Insecticides - therapeutic use
Ivermectin - therapeutic use
Permethrin - pharmacology
Permethrin - therapeutic use
Sarcoptes scabiei
Scabies - drug therapy
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Summary:Reports of permethrin resistance of Sarcoptes scabiei var. hominis are emerging. We propose that this may be pseudoresistance. The resistance is due to inadequate counselling by physicians, incorrect treatment (insufficient quantity of permethrin; too short length of treatment), and poor adherence and compliance by patients. Other reasons include single application of permethrin, suggestion to apply the drug for 6-8 hours, failed application on subungual folds, irritant contact dermatitis, in particular on genitals, for which some patients stop the treatment, and unexplainable use of permethrin in post-scabies prurigo. Thus, we believe that several cases of resistance to permethrin are actually cases of pseudoresistance.
ISSN:1972-2680
2036-6590
1972-2680
DOI:10.3855/jidc.17750