Fused Furan Moieties from Enol-like Compounds and β‑Keto Sulfoxonium Ylides Involving sp2 C–H Activation and Concomitant Tandem C–O Annulation

An efficient and fascinating protocol has been devised for the preparation of fused furan moieties involving a Rh­(II) catalyzed one-pot C–H activation/concomitant tandem annulation process, employing an enolic compound and β-keto sulfoxonium ylide as the reacting conjugates. The developed technique...

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Bibliographic Details
Published in:Organic letters 2023-06, Vol.25 (24), p.4493-4497
Main Authors: Das, Dwaipayan, Das, Agniva, Islam, Saiful, Das, Asish R., Banerjee, Adrita, Majumder, Romit, Bandyopadhyay, Debasish
Format: Article
Language:English
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Summary:An efficient and fascinating protocol has been devised for the preparation of fused furan moieties involving a Rh­(II) catalyzed one-pot C–H activation/concomitant tandem annulation process, employing an enolic compound and β-keto sulfoxonium ylide as the reacting conjugates. The developed technique demands only Rh2(TFA)4 as the catalyst to proceed forward and is devoid of additional metallic or nonmetallic additives. The skeletal transformation of naphthoquinone fused furan to highly decorated naphthoquinone fused indolizines is a promising synthetic application.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.3c01455