Prevalence of Cardiac Amyloidosis in Patients Undergoing Carpal Tunnel Release With Amyloid Deposition

Background: Carpal tunnel syndrome (CTS) is considered an early sign of cardiac amyloidosis (CA) because amyloid deposition is often confirmed in the tenosynovium removed during carpal tunnel release (CTR); however, the prevalence of concomitant CA is unclear.Methods and Results: We prospectively ex...

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Bibliographic Details
Published in:Circulation Journal 2023/07/25, Vol.87(8), pp.1047-1055
Main Authors: Takashio, Seiji, Kato, Teiji, Tashima, Hikaru, Irie, Hiroki, Komohara, Yoshihiro, Oguni, Tetsuya, Morikawa, Kei, Kuyama, Naoto, Tabata, Noriaki, Hanatani, Shinsuke, Yamamoto, Eiichiro, Matsushita, Kenichi, Ueda, Mitsuharu, Tsujita, Kenichi
Format: Article
Language:English
Subjects:
Aged
Amyloid
Amyloidosis - complications
Amyloidosis - diagnostic imaging
Amyloidosis - epidemiology
Cardiac amyloidosis
Carpal tunnel release
Carpal tunnel syndrome
Carpal Tunnel Syndrome - diagnostic imaging
Carpal Tunnel Syndrome - epidemiology
Carpal Tunnel Syndrome - surgery
Female
Humans
Hypertrophy, Left Ventricular - complications
Male
Prevalence
Technetium Tc 99m Pyrophosphate
Tenosynovium
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Summary:Background: Carpal tunnel syndrome (CTS) is considered an early sign of cardiac amyloidosis (CA) because amyloid deposition is often confirmed in the tenosynovium removed during carpal tunnel release (CTR); however, the prevalence of concomitant CA is unclear.Methods and Results: We prospectively examined 700 patients who underwent CTR and evaluated amyloid deposition after tenosynovium removal. Amyloid deposition was observed in 261 (37%) patients, who were significantly older and predominantly male (P
ISSN:1346-9843
1347-4820
1347-4820
DOI:10.1253/circj.CJ-23-0223