A TCF-based fluorescent probe to determine nitroreductase (NTR) activity for a broad-spectrum of bacterial species

A nitroreductase (NTR) responsive fluorescent probe with long wavelength fluorescence emission was used to determine the NTR activity of a selection of bacterial species under a range of different bacterial growth conditions ensuring applicability under multiple complex clinical environments, where...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2023-06, Vol.59 (53), p.8278-8281
Main Authors: Yan, Kai-Cheng, Gardiner, Jordan E, Sedgwick, Adam C, Thet, Naing, Heylen, Rachel A, James, Tony D, Jenkins, A. Toby A, He, Xiao-Peng
Format: Article
Language:English
Subjects:
Fluorescent indicators
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Summary:A nitroreductase (NTR) responsive fluorescent probe with long wavelength fluorescence emission was used to determine the NTR activity of a selection of bacterial species under a range of different bacterial growth conditions ensuring applicability under multiple complex clinical environments, where sensitivity, reaction time, and the detection accuracy were suitable for planktonic cultures and biofilms. A nitroreductase (NTR) responsive fluorescent probe with long wavelength fluorescence emission was used to determine the NTR activity of a selection of bacterial species under a range of different bacterial growth conditions.
ISSN:1359-7345
1364-548X
DOI:10.1039/d3cc00462g