Development process and clinical application of collagenase chemonucleolysis in the treatment of lumbar disc herniation: a narrative review in China

Lumbar disc herniation (LDH) is one of the most common causes of lumbocrural pain. In the past 20 years, the incidence of LDH has increased dramatically. There are many treatments for LDH, including conservative treatment (such as acupuncture and physiotherapy), minimally invasive interventional tre...

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Bibliographic Details
Published in:Postgraduate medical journal 2023-06, Vol.99 (1172), p.529-534
Main Authors: Yuan, Peng, Shi, Xiaohua, Wei, Xuanjun, Wang, Zijun, Mu, Jiao, Zhang, Hongxin
Format: Article
Language:English
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Review
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Summary:Lumbar disc herniation (LDH) is one of the most common causes of lumbocrural pain. In the past 20 years, the incidence of LDH has increased dramatically. There are many treatments for LDH, including conservative treatment (such as acupuncture and physiotherapy), minimally invasive interventional treatment (such as collagenase chemonucleolysis and radiofrequency ablation) and surgical treatment. The main purpose of this paper is to review the development process and application status of collagenase chemonucleolysis in the treatment of LDH at home and abroad and provide a reference for clinical treatment.
ISSN:0032-5473
1469-0756
DOI:10.1136/postgradmedj-2021-141208