Research status and prospect of tissue engineering technology in treatment of atrophic rhinitis

To review the research progress of the feasibility of a new treatment method for atrophic rhinitis (ATR) based on tissue engineering technology (seed cells, scaffold materials, and growth factors), and provide new ideas for the treatment of ATR. The literature related to ATR was extensively reviewed...

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Bibliographic Details
Published in:Zhongguo xiu fu chong jian wai ke za zhi 2023-06, Vol.37 (6), p.727
Main Authors: Lei, Shuting, Hu, Juanjuan, Tang, Yingqi, Gan, Weigang, Song, Yuting, Jiang, Yanlin, Zhang, Honghui, Gao, Yaya, Yang, Hui, Xie, Huiqi
Format: Article
Language:Chinese
Subjects:
Cytokines
Humans
Printing, Three-Dimensional
Rhinitis, Atrophic
Tissue Engineering - methods
Tissue Scaffolds
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Summary:To review the research progress of the feasibility of a new treatment method for atrophic rhinitis (ATR) based on tissue engineering technology (seed cells, scaffold materials, and growth factors), and provide new ideas for the treatment of ATR. The literature related to ATR was extensively reviewed. Focusing on the three aspects of seed cells, scaffold materials, and growth factors, the recent research progress of ATR treatment was reviewed, and the future directions of tissue engineering technology to treat ATR were proposed. The pathogenesis and etiology of ATR are still unclear, and the effectiveness of the current treatments are still unsatisfactory. The construction of a cell-scaffold complex with sustained and controlled release of exogenous cytokines is expected to reverse the pathological changes of ATR, promoting the regeneration of normal nasal mucosa and reconstructing the atrophic turbinate. In recent years, the research progress of exosomes, three-dimensional printing, and organoids will promote
ISSN:1002-1892
DOI:10.7507/1002-1892.202301064