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Catheter-directed therapy for acute pulmonary embolism: results of a multicenter national registry

Catheter-directed therapy (CDT) for acute pulmonary embolism (PE) is an emerging therapy that combines heterogeneous techniques. The aim of the study was to provide a nationwide contemporary snapshot of clinical practice and CDT-related outcomes. This Investigator-initiated multicenter registry aime...

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Published in:Revista española de cardiología (English ed.) 2024-02, Vol.77 (2), p.138-147
Main Authors: Salinas, Pablo, Vázquez-Álvarez, María-Eugenia, Salvatella, Neus, Ruiz Quevedo, Valeriano, Velázquez Martín, Maite, Valero, Ernesto, Rumiz, Eva, Jurado-Román, Alfonso, Lozano, Íñigo, Gallardo, Fernando, Amat-Santos, Ignacio J., Lorenzo, Óscar, Portero Portaz, Juan José, Huanca, Mike, Nombela-Franco, Luis, Vaquerizo, Beatriz, Ramallal Martínez, Raúl, Maneiro Melón, Nicolás Manuel, Sanchis, Juan, Berenguer, Alberto, Gallardo-López, Arsenio, Gutiérrez-Ibañes, Enrique, Mejía-Rentería, Hernán, Córdoba-Soriano, Juan Gabriel, Jiménez-Mazuecos, Jesús María
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Language:English
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Summary:Catheter-directed therapy (CDT) for acute pulmonary embolism (PE) is an emerging therapy that combines heterogeneous techniques. The aim of the study was to provide a nationwide contemporary snapshot of clinical practice and CDT-related outcomes. This Investigator-initiated multicenter registry aimed to include consecutive patients with intermediate-high risk (IHR) or high-risk (HR), acute PE eligible for CDT. The primary outcome of the study was in-hospital all-cause death. A total of 253 patients were included, of whom 93 (36.8%) had HR-PE, and 160 (63.2%) had IHR-PE with a mean age of 62.3±15.1 years. Local thrombolysis was performed in 70.8% and aspiration thrombectomy in 51.8%, with 23.3% of patients receiving both. However, aspiration thrombectomy was favored in the HR-PE cohort (80.6% vs 35%; P
ISSN:1885-5857
1885-5857
DOI:10.1016/j.rec.2023.06.005