Reduced adipose tissue in growth-restricted fetuses using quantitative analysis of magnetic resonance images

Objectives Fat–water MRI can be used to quantify tissues’ lipid content. We aimed to quantify fetal third trimester normal whole-body subcutaneous lipid deposition and explore differences between appropriate for gestational age (AGA), fetal growth restriction (FGR), and small for gestational age fet...

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Bibliographic Details
Published in:European radiology 2023-12, Vol.33 (12), p.9194-9202
Main Authors: Rabinowich, Aviad, Avisdris, Netanell, Zilberman, Ayala, Link-Sourani, Daphna, Lazar, Sapir, Herzlich, Jacky, Specktor-Fadida, Bella, Joskowicz, Leo, Malinger, Gustavo, Ben-Sira, Liat, Hiersch, Liran, Ben Bashat, Dafna
Format: Article
Language:English
Subjects:
Adipose tissue
Body volume (biology)
Criteria
Deposition
Diagnostic Radiology
Fetuses
Gestational age
Image acquisition
Imaging
Internal Medicine
Interventional Radiology
Lipids
Magnetic Resonance
Magnetic resonance imaging
Medical imaging
Medicine
Medicine & Public Health
Neuroradiology
Nutritional status
Parameters
Radiology
Regression analysis
Small for gestational age
Ultrasound
Water stratification
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Summary:Objectives Fat–water MRI can be used to quantify tissues’ lipid content. We aimed to quantify fetal third trimester normal whole-body subcutaneous lipid deposition and explore differences between appropriate for gestational age (AGA), fetal growth restriction (FGR), and small for gestational age fetuses (SGAs). Methods We prospectively recruited women with FGR and SGA-complicated pregnancies and retrospectively recruited the AGA cohort (sonographic estimated fetal weight [EFW] ≥ 10th centile). FGR was defined using the accepted Delphi criteria, and fetuses with an EFW 
ISSN:1432-1084
0938-7994
1432-1084
DOI:10.1007/s00330-023-09855-y