Isolated paravermal T2 high-intensity lesions in dentatorubral–pallidoluysian atrophy

•DRPLA is caused by the expansion of CAG repeats in atrophin 1.•Paravermal lesions are a characteristic MRI finding in late adult-onset DRPLA.•MRI shows cerebellar atrophy after many years along with paravermal lesions.•Paravermal lesions may be the only abnormality in MRI for early DRPLA diagnosis....

Full description

Saved in:
Bibliographic Details
Published in:Journal of the neurological sciences 2023-08, Vol.451, p.120717-120717, Article 120717
Main Authors: Nakagawa, Yuki, Sugiyama, Atsuhiko, Hirano, Shigeki, Ishige, Takayuki, Kuwabara, Satoshi
Format: Article
Language:English
Subjects:
Atrophy - pathology
Brain - pathology
Dentatorubral–pallidoluysian atrophy
Globus Pallidus
Humans
Magnetic resonance imaging
Myoclonic Epilepsies, Progressive - diagnostic imaging
Paravermal lesions
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c305t-a041b8129526ab9ad439ca11113b48c05757bc78a1906da192199ef58b0829d43
container_end_page 120717
container_issue
container_start_page 120717
container_title Journal of the neurological sciences
container_volume 451
creator Nakagawa, Yuki
Sugiyama, Atsuhiko
Hirano, Shigeki
Ishige, Takayuki
Kuwabara, Satoshi
description •DRPLA is caused by the expansion of CAG repeats in atrophin 1.•Paravermal lesions are a characteristic MRI finding in late adult-onset DRPLA.•MRI shows cerebellar atrophy after many years along with paravermal lesions.•Paravermal lesions may be the only abnormality in MRI for early DRPLA diagnosis.
doi_str_mv 10.1016/j.jns.2023.120717
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2832575358</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0022510X23001788</els_id><sourcerecordid>2832575358</sourcerecordid><originalsourceid>FETCH-LOGICAL-c305t-a041b8129526ab9ad439ca11113b48c05757bc78a1906da192199ef58b0829d43</originalsourceid><addsrcrecordid>eNp9kD1uGzEQRonAQaw4OYAbY0s3qwxJUcuFK8PIjwEDaRwkHTHLHUUUKHJNcg2oyx1yw5wkNGSnzBQzzfs-YB5j5xyWHPj6w265C3kpQMglF9Dx7hVbcN3pVmktT9gCQIhWcfhxyt7mvAOAtdb9G3YqO6kVCL1g329z9FhobCZM-Ehpj765F83W_dy2LhQK2ZVD4ym7GHLjQjNSKFhimoeE_s-v3xN678bo50N2GBosKU7bwzv2eoM-0_vne8a-ffp4f_Olvfv6-fbm-q61ElRpEVZ80Fz0Sqxx6HFcyd4iryOHlbagOtUNttPIe1iPdQve97RRegAt-kqfsctj75Tiw0y5mL3LlrzHQHHORmgpaolUuqL8iNoUc060MVNye0wHw8E8-TQ7U32aJ5_m6LNmLp7r52FP47_Ei8AKXB0Bqk8-OkomW0fB0ugS2WLG6P5T_xcVhoc2</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2832575358</pqid></control><display><type>article</type><title>Isolated paravermal T2 high-intensity lesions in dentatorubral–pallidoluysian atrophy</title><source>ScienceDirect Freedom Collection 2022-2024</source><creator>Nakagawa, Yuki ; Sugiyama, Atsuhiko ; Hirano, Shigeki ; Ishige, Takayuki ; Kuwabara, Satoshi</creator><creatorcontrib>Nakagawa, Yuki ; Sugiyama, Atsuhiko ; Hirano, Shigeki ; Ishige, Takayuki ; Kuwabara, Satoshi</creatorcontrib><description>•DRPLA is caused by the expansion of CAG repeats in atrophin 1.•Paravermal lesions are a characteristic MRI finding in late adult-onset DRPLA.•MRI shows cerebellar atrophy after many years along with paravermal lesions.•Paravermal lesions may be the only abnormality in MRI for early DRPLA diagnosis.</description><identifier>ISSN: 0022-510X</identifier><identifier>EISSN: 1878-5883</identifier><identifier>DOI: 10.1016/j.jns.2023.120717</identifier><identifier>PMID: 37385028</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Atrophy - pathology ; Brain - pathology ; Dentatorubral–pallidoluysian atrophy ; Globus Pallidus ; Humans ; Magnetic resonance imaging ; Myoclonic Epilepsies, Progressive - diagnostic imaging ; Paravermal lesions</subject><ispartof>Journal of the neurological sciences, 2023-08, Vol.451, p.120717-120717, Article 120717</ispartof><rights>2023 Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c305t-a041b8129526ab9ad439ca11113b48c05757bc78a1906da192199ef58b0829d43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37385028$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nakagawa, Yuki</creatorcontrib><creatorcontrib>Sugiyama, Atsuhiko</creatorcontrib><creatorcontrib>Hirano, Shigeki</creatorcontrib><creatorcontrib>Ishige, Takayuki</creatorcontrib><creatorcontrib>Kuwabara, Satoshi</creatorcontrib><title>Isolated paravermal T2 high-intensity lesions in dentatorubral–pallidoluysian atrophy</title><title>Journal of the neurological sciences</title><addtitle>J Neurol Sci</addtitle><description>•DRPLA is caused by the expansion of CAG repeats in atrophin 1.•Paravermal lesions are a characteristic MRI finding in late adult-onset DRPLA.•MRI shows cerebellar atrophy after many years along with paravermal lesions.•Paravermal lesions may be the only abnormality in MRI for early DRPLA diagnosis.</description><subject>Atrophy - pathology</subject><subject>Brain - pathology</subject><subject>Dentatorubral–pallidoluysian atrophy</subject><subject>Globus Pallidus</subject><subject>Humans</subject><subject>Magnetic resonance imaging</subject><subject>Myoclonic Epilepsies, Progressive - diagnostic imaging</subject><subject>Paravermal lesions</subject><issn>0022-510X</issn><issn>1878-5883</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9kD1uGzEQRonAQaw4OYAbY0s3qwxJUcuFK8PIjwEDaRwkHTHLHUUUKHJNcg2oyx1yw5wkNGSnzBQzzfs-YB5j5xyWHPj6w265C3kpQMglF9Dx7hVbcN3pVmktT9gCQIhWcfhxyt7mvAOAtdb9G3YqO6kVCL1g329z9FhobCZM-Ehpj765F83W_dy2LhQK2ZVD4ym7GHLjQjNSKFhimoeE_s-v3xN678bo50N2GBosKU7bwzv2eoM-0_vne8a-ffp4f_Olvfv6-fbm-q61ElRpEVZ80Fz0Sqxx6HFcyd4iryOHlbagOtUNttPIe1iPdQve97RRegAt-kqfsctj75Tiw0y5mL3LlrzHQHHORmgpaolUuqL8iNoUc060MVNye0wHw8E8-TQ7U32aJ5_m6LNmLp7r52FP47_Ei8AKXB0Bqk8-OkomW0fB0ugS2WLG6P5T_xcVhoc2</recordid><startdate>20230815</startdate><enddate>20230815</enddate><creator>Nakagawa, Yuki</creator><creator>Sugiyama, Atsuhiko</creator><creator>Hirano, Shigeki</creator><creator>Ishige, Takayuki</creator><creator>Kuwabara, Satoshi</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20230815</creationdate><title>Isolated paravermal T2 high-intensity lesions in dentatorubral–pallidoluysian atrophy</title><author>Nakagawa, Yuki ; Sugiyama, Atsuhiko ; Hirano, Shigeki ; Ishige, Takayuki ; Kuwabara, Satoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c305t-a041b8129526ab9ad439ca11113b48c05757bc78a1906da192199ef58b0829d43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Atrophy - pathology</topic><topic>Brain - pathology</topic><topic>Dentatorubral–pallidoluysian atrophy</topic><topic>Globus Pallidus</topic><topic>Humans</topic><topic>Magnetic resonance imaging</topic><topic>Myoclonic Epilepsies, Progressive - diagnostic imaging</topic><topic>Paravermal lesions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nakagawa, Yuki</creatorcontrib><creatorcontrib>Sugiyama, Atsuhiko</creatorcontrib><creatorcontrib>Hirano, Shigeki</creatorcontrib><creatorcontrib>Ishige, Takayuki</creatorcontrib><creatorcontrib>Kuwabara, Satoshi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the neurological sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nakagawa, Yuki</au><au>Sugiyama, Atsuhiko</au><au>Hirano, Shigeki</au><au>Ishige, Takayuki</au><au>Kuwabara, Satoshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Isolated paravermal T2 high-intensity lesions in dentatorubral–pallidoluysian atrophy</atitle><jtitle>Journal of the neurological sciences</jtitle><addtitle>J Neurol Sci</addtitle><date>2023-08-15</date><risdate>2023</risdate><volume>451</volume><spage>120717</spage><epage>120717</epage><pages>120717-120717</pages><artnum>120717</artnum><issn>0022-510X</issn><eissn>1878-5883</eissn><abstract>•DRPLA is caused by the expansion of CAG repeats in atrophin 1.•Paravermal lesions are a characteristic MRI finding in late adult-onset DRPLA.•MRI shows cerebellar atrophy after many years along with paravermal lesions.•Paravermal lesions may be the only abnormality in MRI for early DRPLA diagnosis.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>37385028</pmid><doi>10.1016/j.jns.2023.120717</doi><tpages>1</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0022-510X
ispartof Journal of the neurological sciences, 2023-08, Vol.451, p.120717-120717, Article 120717
issn 0022-510X
1878-5883
language eng
recordid cdi_proquest_miscellaneous_2832575358
source ScienceDirect Freedom Collection 2022-2024
subjects Atrophy - pathology
Brain - pathology
Dentatorubral–pallidoluysian atrophy
Globus Pallidus
Humans
Magnetic resonance imaging
Myoclonic Epilepsies, Progressive - diagnostic imaging
Paravermal lesions
title Isolated paravermal T2 high-intensity lesions in dentatorubral–pallidoluysian atrophy
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T21%3A55%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Isolated%20paravermal%20T2%20high-intensity%20lesions%20in%20dentatorubral%E2%80%93pallidoluysian%20atrophy&rft.jtitle=Journal%20of%20the%20neurological%20sciences&rft.au=Nakagawa,%20Yuki&rft.date=2023-08-15&rft.volume=451&rft.spage=120717&rft.epage=120717&rft.pages=120717-120717&rft.artnum=120717&rft.issn=0022-510X&rft.eissn=1878-5883&rft_id=info:doi/10.1016/j.jns.2023.120717&rft_dat=%3Cproquest_cross%3E2832575358%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c305t-a041b8129526ab9ad439ca11113b48c05757bc78a1906da192199ef58b0829d43%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2832575358&rft_id=info:pmid/37385028&rfr_iscdi=true