A high-resolution SPECT system based on a microchannel-plate imager

The authors have developed a high-resolution single-photon emission computed tomography (SPECT) system for small-animal studies with /sup 125/I. The SPECT camera uses a Hamamatsu microchannel-plate imager PIAS (photon-counting image acquisition system), a 0.7-mm-thick NaI(Tl) plate, and a lead-glass...

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Bibliographic Details
Published in:IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (USA) 1990-04, Vol.37 (2), p.687-695
Main Authors: Dilmanian, F.A., Weber, D.A., Coderre, J.A., Joel, D.D., Shi, K.-C., Meinken, G.E., Som, P., Tang, Y.-N., Volkow, N.D., Yee, C., Brill, A.B., Watanabe, M., Inuzuka, E., Oba, K., Gerson, R., Iida, H., Hiruma, A.
Format: Article
Language:English
Subjects:
07 ISOTOPES AND RADIATION SOURCES
550601 > Medicine-- Unsealed Radionuclides in Diagnostics
655002 > Medical Physics-- Radiation Source Calibration & Standardization
655003 > Medical Physics-- Dosimetry
BETA DECAY RADIOISOTOPES
CAMERAS
COLLIMATORS
Computed tomography
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DESIGN
DIAGNOSTIC TECHNIQUES
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
EMISSION COMPUTED TOMOGRAPHY
Face detection
FIBERS
GAMMA CAMERAS
Gamma ray detection
Gamma ray detectors
IMAGE PROCESSING
Image reconstruction
Image resolution
IMAGE SCANNERS
INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPES
LEAD
MEASURING INSTRUMENTS
METALS
MOCKUP
NAI DETECTORS
NUCLEI
ODD-EVEN NUCLEI
Optical collimators
OPTICAL FIBERS
PHANTOMS
PROCESSING
RADIATION DETECTORS
RADIATION PROTECTION AND DOSIMETRY
RADIOISOTOPES
RADIOLOGY AND NUCLEAR MEDICINE
SCINTILLATION COUNTERS
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
SOLID SCINTILLATION DETECTORS
STRUCTURAL MODELS
TOMOGRAPHY 440103 > Radiation Instrumentation-- Nuclear Spectroscopic Instrumentation
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Summary:The authors have developed a high-resolution single-photon emission computed tomography (SPECT) system for small-animal studies with /sup 125/I. The SPECT camera uses a Hamamatsu microchannel-plate imager PIAS (photon-counting image acquisition system), a 0.7-mm-thick NaI(Tl) plate, and a lead-glass parallel-hole collimator. The 15-mm-diameter field of view (FOV) of the PIAS tube was enlarged by an optical fiber faceplate taper to provide a 26-mm camera FOV. Camera absolute sensitivity (counts detected/gamma photons emitted) is 2*10/sup -5/ for /sup 125/I. The system provides an in-plane resolution of about 0.7 mm FWHM (full width at half maximum) in the reconstructed image for a 15-mm radius of rotation. SPECT images from phantom studies and from organs in the rat and mouse provide examples of the resolving capacity of the system.< >
ISSN:0018-9499
1558-1578
DOI:10.1109/23.106699