A lack of commitment to proliferation

It turns out that commitment to cell division is not an irreversible switch. In the absence of sustained stimulation by growth factor proteins during DNA replication, cells can quit the cell cycle before cell division occurs. Commitment to cell division is not an irreversible switch.

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Bibliographic Details
Published in:Nature (London) 2023-07, Vol.619 (7969), p.257-258
Main Author: Barr, Alexis R.
Format: Article
Language:English
Subjects:
631/67
631/80
Cell cycle
Cell Differentiation
Cell division
Cell growth
Cell Proliferation
Deoxyribonucleic acid
DNA
DNA biosynthesis
Genomes
Growth factors
Humanities and Social Sciences
Molecular machines
multidisciplinary
News And Views
Proteins
Replication
Science
Citations: Items that this one cites
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Description
Summary:It turns out that commitment to cell division is not an irreversible switch. In the absence of sustained stimulation by growth factor proteins during DNA replication, cells can quit the cell cycle before cell division occurs. Commitment to cell division is not an irreversible switch.
ISSN:0028-0836
1476-4687
DOI:10.1038/d41586-023-02136-0