A basket genetic trial of the vasculitides

The rarity of various forms of vasculitis, as well as other rheumatic diseases, presents difficulties in studying the genetics of these diseases as well as for evaluating treatments. Might new approaches, such as joint genetic analyses and drug repurposing, provide opportunities to learn more about...

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Bibliographic Details
Published in:Nature reviews. Rheumatology 2023-09, Vol.19 (9), p.541-542
Main Authors: Carnero-Montoro, Elena, Alarcón-Riquelme, Marta E.
Format: Article
Language:English
Subjects:
692/4023/1670
692/4023/1670/595
692/420/2489/144
Apoptosis
Arthritis
Cancer therapies
Clinical trials
COVID-19
Genetic analysis
Genomics
Health risk assessment
Kinases
Lupus
Medical research
Medicine
Medicine & Public Health
News & Views
news-and-views
Rheumatic diseases
Rheumatology
Vasculitis
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Description
Summary:The rarity of various forms of vasculitis, as well as other rheumatic diseases, presents difficulties in studying the genetics of these diseases as well as for evaluating treatments. Might new approaches, such as joint genetic analyses and drug repurposing, provide opportunities to learn more about these diseases and identify new therapies and serve as a basis for basket clinical trials?
ISSN:1759-4790
1759-4804
DOI:10.1038/s41584-023-00996-4