Sex- and timing-specific effects of fasting and caloric restriction

Optimizing food quantity and fasting time may improve health and lifespan. We summarize emerging knowledge on sex, age, and circadian timing as important determinants for the efficacy of dietary interventions and highlight results from Duregon et al. pointing to a favorable combination of caloric re...

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Bibliographic Details
Published in:Cell metabolism 2023-07, Vol.35 (7), p.1091-1093
Main Authors: Hofer, Sebastian J., Madeo, Frank
Format: Article
Language:English
Subjects:
Animals
Caloric Restriction
Fasting
Female
Longevity
Mice
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Summary:Optimizing food quantity and fasting time may improve health and lifespan. We summarize emerging knowledge on sex, age, and circadian timing as important determinants for the efficacy of dietary interventions and highlight results from Duregon et al. pointing to a favorable combination of caloric restriction (CR) and fasting in aged female mice. Optimizing food quantity and fasting time may improve health and lifespan. We summarize emerging knowledge on sex, age, and circadian timing as important determinants for the efficacy of dietary interventions and highlight results from Duregon et al. pointing to a favorable combination of caloric restriction (CR) and fasting in aged female mice.
ISSN:1550-4131
1932-7420
DOI:10.1016/j.cmet.2023.06.001