Massage therapy significantly improves cancer-related fatigue in cancer patients: a meta-analysis of randomized controlled trials

Purpose This study was designed to investigate the effectiveness and safety of massage therapy in cancer-related fatigue (CRF) and to provide a reference for the future management of CRF. Methods Eight databases (PubMed, Embase, Cochrane Library, CINAHL, Sinomed, Chinese Scientific Journal database...

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Bibliographic Details
Published in:Supportive care in cancer 2023-08, Vol.31 (8), p.464-464, Article 464
Main Authors: Shan, Shengnan, Lin, Lu, Fang, Qian, Tian, Fengmei, Guo, Daoxia, Zhou, Yanling, Tian, Li
Format: Article
Language:English
Subjects:
Analysis
Breast cancer
Breast Neoplasms - therapy
Cancer
Cancer patients
Care and treatment
Clinical outcomes
Clinical trials
Fatigue
Fatigue - etiology
Fatigue - therapy
Female
Health aspects
Humans
Massage
Medicine
Medicine & Public Health
Meta-analysis
Mind-Body Therapies
Nursing
Nursing Research
Oncology
Oncology, Experimental
Pain Medicine
Randomized Controlled Trials as Topic
Reflexology
Rehabilitation Medicine
Review
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Summary:Purpose This study was designed to investigate the effectiveness and safety of massage therapy in cancer-related fatigue (CRF) and to provide a reference for the future management of CRF. Methods Eight databases (PubMed, Embase, Cochrane Library, CINAHL, Sinomed, Chinese Scientific Journal database (VIP), Wanfang, and China National Knowledge Infrastructure (CNKI)) were systematically reviewed from inception to May 2022 for randomized controlled trials. Two reviewers critically and independently assessed the risk of bias using Cochrane Collaboration criteria and extracted correlated data using the designed form. The meta-analysis was performed using RevMan 5.3 to calculate the pooled effect sizes and 95% confidence intervals (CIs). Sensitivity analysis was performed to find the source of the heterogeneity. Publication bias was assessed via funnel plot analysis and the Egger test. Result A total of 11 qualified studies that included 789 patients (massage therapy group: 389; control group: 400) were included in the meta-analysis. Massage therapy had a marked effect on fatigue in cancer patients [standardized mean difference (SMD) =  − 1.69, 95% CI (− 2.46, − 0.93), P  
ISSN:0941-4355
1433-7339
DOI:10.1007/s00520-023-07926-w