Antibiofilm and antimicrobial activity of Lactobacillus cell free supernatant against Pseudomonas aeruginosa isolated from burn wounds

The present study investigated the antimicrobial and anti‐biofilm effects of indigenous Lactobacillus probiotic strains on Pseudomonas aeruginosa isolated from burn wound infection in laboratory conditions. The effect of 7 probiotic strains isolated from infant faeces on the pathogenicity factors of...

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Bibliographic Details
Published in:International wound journal 2023-12, Vol.20 (10), p.4112-4121
Main Authors: Asadzadegan, Reza, Haratian, Negar, Sadeghi, Mahsa, Maroufizadeh, Saman, Mobayen, Mohammadreza, Sedigh Ebrahim Saraei, Hadi, Hasannejad‐Bibalan, Meysam
Format: Article
Language:English
Subjects:
Antibiotics
Antimicrobial agents
Bacteria
Biofilms
burns
Immune system
Infections
Lactobacillus
Pathogens
Probiotics
Pseudomonas aeruginosa
wounds and injuries
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Summary:The present study investigated the antimicrobial and anti‐biofilm effects of indigenous Lactobacillus probiotic strains on Pseudomonas aeruginosa isolated from burn wound infection in laboratory conditions. The effect of 7 probiotic strains isolated from infant faeces on the pathogenicity factors of P. aeruginosa, including protease, elastase, antibiofilm and antipyocyanin was measured. Also, diffusion methods in the well and micro broth dilution were used to evaluate the antimicrobial activity of probiotics. All tests were performed in triplicate. A negative control and a positive control were used for each test. SPSS version 22 software was used for statistical analysis, and a p 
ISSN:1742-4801
1742-481X
DOI:10.1111/iwj.14305