Increased risk of depression in patients with discoid lupus erythematosus: a nested, case-control study in the All of Us Research Program

In this nested case–control study, we found a twofold increased risk of major depressive disorder in patients with discoid lupus erythematosus (DLE) vs. controls without DLE, using the All of Us database, a National Institutes of Health (USA) research programme that prioritizes recruitment from demo...

Full description

Saved in:
Bibliographic Details
Published in:British journal of dermatology (1951) 2023-10, Vol.189 (5), p.628-629
Main Authors: Chen, Gloria F, Shaw, Katharina S, Sanchez-Melendez, Stephanie, Vleugels, Ruth Ann, Cohen, Jeffrey M
Format: Article
Language:English
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this nested case–control study, we found a twofold increased risk of major depressive disorder in patients with discoid lupus erythematosus (DLE) vs. controls without DLE, using the All of Us database, a National Institutes of Health (USA) research programme that prioritizes recruitment from demographic groups under-represented in biomedical research. This is the first large-scale study of this association in a heterogeneous population and highlights the importance vigilance regarding the increased risk of depression in patients with DLE.
ISSN:0007-0963
1365-2133
DOI:10.1093/bjd/ljad239