Resting state EEG rhythms in different stages of chronic kidney disease with mild cognitive impairment

Here, we tested that standard eyes-closed resting-state electroencephalographic (rsEEG) rhythms may characterize patients with mild cognitive impairment due to chronic kidney disease at stages 3–4 (CKDMCI-3&4) in relation to CKDMCI patients under hemodialysis (CKDMCI-H) and mild cognitive impair...

Full description

Saved in:
Bibliographic Details
Published in:Neurobiology of aging 2023-10, Vol.130, p.70-79
Main Authors: Lizio, Roberta, Lopez, Susanna, Babiloni, Claudio, Del Percio, Claudio, Noce, Giuseppe, Losurdo, Antonia, Vernò, Lucia, De Tommaso, Marina, Montemurno, Anna, Dalfino, Giuseppe, Cirillo, Pietro, Soricelli, Andrea, Ferri, Raffaele, Catania, Valentina, Nobili, Flavio, Giubilei, Franco, Buttinelli, Carla, Frisoni, Giovanni B., Stocchi, Fabrizio, Scisci, Anna Maria, Mastrofilippo, Nicola, Procaccini, Deni Aldo, Gesualdo, Loreto
Format: Article
Language:English
Subjects:
Alzheimer Disease - psychology
Brain
Cerebral Cortex - physiology
Cerebrovascular disease
Chronic kidney disease (CKD)
Cognitive Dysfunction - etiology
Electroencephalography - methods
Hemodialysis
Humans
Mild cognitive impairment (MCI)
Renal Insufficiency, Chronic
Rest - physiology
Resting-state electroencephalographic (rsEEG) rhythms
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Here, we tested that standard eyes-closed resting-state electroencephalographic (rsEEG) rhythms may characterize patients with mild cognitive impairment due to chronic kidney disease at stages 3–4 (CKDMCI-3&4) in relation to CKDMCI patients under hemodialysis (CKDMCI-H) and mild cognitive impairment (MCI) patients with cerebrovascular disease (CVMCI). Clinical and rsEEG data in 22 CKDMCI-3&4, 15 CKDMCI-H, 18 CVMCI, and 30 matched healthy control (HC) participants were available in a national archive. Spectral rsEEG power density was calculated from delta to gamma frequency bands at scalp electrodes. Results showed that (1) all MCI groups over the HC group showed decreased occipital rsEEG alpha power density; (2) compared to the HC and CVMCI groups, the 2 CKDMCI groups had higher rsEEG delta–theta power density; and (3) the CKDMCI-3&4 group showed the lowest parietal rsEEG alpha power density. The present rsEEG measures may be useful to monitor the impact of circulating uremic toxins on brain regulation of cortical arousal for quiet vigilance in CKDMCI patients.
ISSN:0197-4580
1558-1497
1558-1497
DOI:10.1016/j.neurobiolaging.2023.05.014