Advance Consent in Acute Stroke Trials: Survey of Canadian Research Ethics Board Chairs

Advance consent could allow individuals at high risk of stroke to provide consent before they might become eligible for enrollment in acute stroke trials. This survey explores the acceptability of this novel technique to Canadian Research Ethics Board (REB) chairs that review acute stroke trials. Re...

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Bibliographic Details
Published in:Canadian journal of neurological sciences 2024-03, Vol.51 (2), p.285-288
Main Authors: Seeger, Rena, Udoh, Ubong, Dewar, Brian, Nicholls, Stuart, Fedyk, Mark, Fahed, Robert, Perry, Jeff, Hill, Michael D., Menon, Bijoy, Swartz, Richard H., Poppe, Alexandre Y., Gocan, Sophia, Brehaut, Jamie, Dainty, Katie, Shepherd, Victoria, Dowlatshahi, Dar, Shamy, Michel
Format: Article
Language:English
Subjects:
Brief Communication
Clinical trials
Emergency medical care
Informed consent
Patients
Polls & surveys
Research ethics
Response rates
Stroke
Citations: Items that this one cites
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Summary:Advance consent could allow individuals at high risk of stroke to provide consent before they might become eligible for enrollment in acute stroke trials. This survey explores the acceptability of this novel technique to Canadian Research Ethics Board (REB) chairs that review acute stroke trials. Responses from 15 REB chairs showed that majority of respondents expressed comfort approving studies that adopt advance consent. There was no clear preference for advance consent over deferral of consent, although respondents expressed significant concern with broad rather than trial-specific advance consent. These findings shed light on the acceptability of advance consent to Canadian ethics regulators.
ISSN:0317-1671
2057-0155
DOI:10.1017/cjn.2023.247