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Ten years of Italian mini-invasiveness: the I Go MILS registry as a tool of dissemination, characterization and networking
Purposes of this study are to evaluate the main changes that have occurred in the Italian MILS activity in the last decade in terms of indications, approaches and outcomes as reported in the national registry and to provide specific details on the main areas of development of MILS. Data from patient...
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Published in: | Updates in surgery 2023-09, Vol.75 (6), p.1457-1469 |
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creator | Ratti, Francesca Ferrero, Alessandro Guglielmi, Alfredo Cillo, Umberto Giuliante, Felice Mazzaferro, Vincenzo De Carlis, Luciano Ettorre, Giuseppe Maria Gruttadauria, Salvatore Di Benedetto, Fabrizio Ercolani, Giorgio Valle, Raffaele Dalla Belli, Andrea Jovine, Elio Ravaioli, Matteo Aldrighetti, Luca |
description | Purposes of this study are to evaluate the main changes that have occurred in the Italian MILS activity in the last decade in terms of indications, approaches and outcomes as reported in the national registry and to provide specific details on the main areas of development of MILS. Data from patients undergoing minimally invasive liver resections at centers included in the I Go MILS Registry from its start-up (November 2014) to March 2023 were analyzed for the purposes of this study. The registry is intention-to-treat and prospective. Global recruitment trends stratified by indication to surgery and type of approach were analysed. 7413 MILS procedures were performed across all centers (median number of procedures per center: 63). Years (2020–2023) displayed a significantly higher proportion of treated patients diagnosed with hepatocellular carcinoma (HCC) (38.2% vs. 28.9% and 33.9%,
p
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doi_str_mv | 10.1007/s13304-023-01597-2 |
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p
< 0.001) and cholangiocarcinoma (6.7% vs. 6.5% and 4.2%,
p
< 0.001) compared to the preceding triennial periods. Additionally, technical complexity demonstrated an increased prominence in Years (2019–2023) with a significantly higher percentage of grade III cases compared to the earlier periods (39.3% vs. 21.7% and 25.6%,
p
< 0.001). Annual case trends focusing on laparoscopic and robotic techniques demonstrated a steadily increase in the use of these techniques for complex case mix of indications. Overall, attitude and attention to MILS approach has evolved, so that currently indications to hepatic mini-invasiveness have expanded and surgical technique has been refined: Areas mainly involved in increasing growth trends are hepatocellular carcinoma, possible applications of MILS in transplant setting, intrahepatic cholangiocarcinoma and robotic approach.</description><identifier>ISSN: 2038-131X</identifier><identifier>EISSN: 2038-3312</identifier><identifier>DOI: 10.1007/s13304-023-01597-2</identifier><identifier>PMID: 37488408</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Medicine ; Medicine & Public Health ; Original Article ; Surgery</subject><ispartof>Updates in surgery, 2023-09, Vol.75 (6), p.1457-1469</ispartof><rights>Italian Society of Surgery (SIC) 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. Italian Society of Surgery (SIC).</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-e10f210e80afe13cfd0d48b15a0e566be3e2d3d3e169c9fa534091c21c1a76443</citedby><cites>FETCH-LOGICAL-c414t-e10f210e80afe13cfd0d48b15a0e566be3e2d3d3e169c9fa534091c21c1a76443</cites><orcidid>0000-0002-8108-9064</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37488408$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ratti, Francesca</creatorcontrib><creatorcontrib>Ferrero, Alessandro</creatorcontrib><creatorcontrib>Guglielmi, Alfredo</creatorcontrib><creatorcontrib>Cillo, Umberto</creatorcontrib><creatorcontrib>Giuliante, Felice</creatorcontrib><creatorcontrib>Mazzaferro, Vincenzo</creatorcontrib><creatorcontrib>De Carlis, Luciano</creatorcontrib><creatorcontrib>Ettorre, Giuseppe Maria</creatorcontrib><creatorcontrib>Gruttadauria, Salvatore</creatorcontrib><creatorcontrib>Di Benedetto, Fabrizio</creatorcontrib><creatorcontrib>Ercolani, Giorgio</creatorcontrib><creatorcontrib>Valle, Raffaele Dalla</creatorcontrib><creatorcontrib>Belli, Andrea</creatorcontrib><creatorcontrib>Jovine, Elio</creatorcontrib><creatorcontrib>Ravaioli, Matteo</creatorcontrib><creatorcontrib>Aldrighetti, Luca</creatorcontrib><creatorcontrib>Italian Group of Minimally Invasive Liver Surgery (I Go MILS)</creatorcontrib><creatorcontrib>on behalf of the Italian Group of Minimally Invasive Liver Surgery (I Go MILS)</creatorcontrib><title>Ten years of Italian mini-invasiveness: the I Go MILS registry as a tool of dissemination, characterization and networking</title><title>Updates in surgery</title><addtitle>Updates Surg</addtitle><addtitle>Updates Surg</addtitle><description>Purposes of this study are to evaluate the main changes that have occurred in the Italian MILS activity in the last decade in terms of indications, approaches and outcomes as reported in the national registry and to provide specific details on the main areas of development of MILS. Data from patients undergoing minimally invasive liver resections at centers included in the I Go MILS Registry from its start-up (November 2014) to March 2023 were analyzed for the purposes of this study. The registry is intention-to-treat and prospective. Global recruitment trends stratified by indication to surgery and type of approach were analysed. 7413 MILS procedures were performed across all centers (median number of procedures per center: 63). Years (2020–2023) displayed a significantly higher proportion of treated patients diagnosed with hepatocellular carcinoma (HCC) (38.2% vs. 28.9% and 33.9%,
p
< 0.001) and cholangiocarcinoma (6.7% vs. 6.5% and 4.2%,
p
< 0.001) compared to the preceding triennial periods. Additionally, technical complexity demonstrated an increased prominence in Years (2019–2023) with a significantly higher percentage of grade III cases compared to the earlier periods (39.3% vs. 21.7% and 25.6%,
p
< 0.001). Annual case trends focusing on laparoscopic and robotic techniques demonstrated a steadily increase in the use of these techniques for complex case mix of indications. 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p
< 0.001) and cholangiocarcinoma (6.7% vs. 6.5% and 4.2%,
p
< 0.001) compared to the preceding triennial periods. Additionally, technical complexity demonstrated an increased prominence in Years (2019–2023) with a significantly higher percentage of grade III cases compared to the earlier periods (39.3% vs. 21.7% and 25.6%,
p
< 0.001). Annual case trends focusing on laparoscopic and robotic techniques demonstrated a steadily increase in the use of these techniques for complex case mix of indications. Overall, attitude and attention to MILS approach has evolved, so that currently indications to hepatic mini-invasiveness have expanded and surgical technique has been refined: Areas mainly involved in increasing growth trends are hepatocellular carcinoma, possible applications of MILS in transplant setting, intrahepatic cholangiocarcinoma and robotic approach.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>37488408</pmid><doi>10.1007/s13304-023-01597-2</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0002-8108-9064</orcidid></addata></record> |
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subjects | Medicine Medicine & Public Health Original Article Surgery |
title | Ten years of Italian mini-invasiveness: the I Go MILS registry as a tool of dissemination, characterization and networking |
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