Predictive value of serum lncRNA MALAT1 for the recurrence of persistent atrial fibrillation after radiofrequency ablation

The authors investigated the predictive value of for persistent atrial fibrillation (PAF) recurrence after radiofrequency ablation. Serum level was determined. The correlation between and high-sensitivity C-reactive protein/left atrial diameter (LAD) was analyzed. The predictive value of MALAT1 was...

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Bibliographic Details
Published in:Biomarkers in medicine 2023-04, Vol.17 (8), p.417-426
Main Authors: Chen, Jiulin, Zhou, Wei, Chen, Jingjing, Zhou, Haiyan, Chen, Zhangrong, Si, Xiaoyun, Zhou, Bo, Yan, Fei, Li, Wei
Format: Article
Language:English
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Summary:The authors investigated the predictive value of for persistent atrial fibrillation (PAF) recurrence after radiofrequency ablation. Serum level was determined. The correlation between and high-sensitivity C-reactive protein/left atrial diameter (LAD) was analyzed. The predictive value of MALAT1 was evaluated. The postoperative recurrence rate in patients with high/low was compared. Independent risk factors for postoperative recurrence were analyzed. was elevated in PAF patients and positively correlated with high-sensitivity C-reactive protein/LAD. /high-sensitivity C-reactive protein/LAD were enhanced in patients with recurrent PAF. Patients with high had a higher recurrence rate. Upregulated was an independent risk factor for postoperative PAF recurrence. Serum level >2.03 predicts postoperative recurrence of PAF, and PAF patients with high have a higher risk of postoperative recurrence.
ISSN:1752-0363
1752-0371
DOI:10.2217/bmm-2022-0697