Comparative valuation of the chlorpyrifos, acetamiprid, and lambda-cyhalothrin toxicity and their hematological and histopathological consequences in pigeons

• Published in: Environmental science and pollution research international 2023-08, Vol.30 (40), p.92817-92829
• Main Authors: Noreen, Shumaila, Khan, Ibrar Muhammad, Khan, Muhammad Shehzad, Zarnaab, Bibi, Gul, Iram, Khan, Muhammad Zahoor, Jadoon, Waqar Azeem, Ghayyur, Shehzad, Liu, Yong
• Format: Article
• Language: English
• Subjects: Agricultural industry; Agrochemicals; Animals; Aquatic Pollution; Atmospheric Protection/Air Quality Control/Air Pollution; Birds; Body weight; Cell size; Chlorpyrifos; Chlorpyrifos - toxicity; Columbidae; Cyhalothrin; Degeneration; Earth and Environmental Science; Ecosystem; Ecotoxicology; Edema; Environment; Environmental Chemistry; Environmental Health; Environmental science; Erythrocytes; Exposure; Glomerulus; Goblet cells; Health risks; Hemoglobin; Humans; Insecticides; Insecticides - toxicity; Leukocytes; Lymphocytes; Necrosis; Pesticide toxicity; Pesticides; Pesticides - toxicity; Pigeons; Renal tubules; Research Article; Toxicity; Toxicology; Waste Water Technology; Water Management; Water Pollution Control; Wildlife
• ISSN: 1614-7499; 0944-1344; 1614-7499
• DOI: 10.1007/s11356-023-28515-8

Globally agrochemicals are widely used in the agricultural sectors, posing potential eco-toxicological risks and disrupting various lifeforms including birds. Thus, the current work was conducted to compare the acute toxic impacts of pesticides (e.g., chlorpyrifos, acetamiprid, and lambda-cyhalothrin) on the pigeon’s health. In total 50 adult pigeons were purchased from a local market where these pigeons were fed on pollution-free food. Post adaptation period (15 days), the pigeons were arbitrarily separated into five distinct groups after having been identified in this manner by chance (each group containing 10 pigeons). Control group (group 1) was not treated with any pesticide while the remaining groups (groups 2, 3, and 4) were treated with 0.25-mg/kg body weight of chlorpyrifos, acetamiprid, lambda-cyhalothrin, and a mixture of all three pesticides (group 5), respectively. After 36 days of exposure, the groups that had been exposed to the pesticide showed a significant ( p < 0.05) increase in both the total number of platelets and the number of white blood cells (WBCs), in comparison to the control group. On the other hand, the groups that were exposed to the insecticides had significantly lower levels of red blood cells (RBCs), hemoglobin (Hb), and packed cell volume (PCV) ( p < 0.05). The value of mean corpuscular volume (MCV) was significantly ( p < 0.05) reduced in acetamiprid-exposed group, while a significant increase was observed in other pesticide-exposed groups. Obvious histopathological changes were observed in the tissues of control group and no such changes were reported by control group. Necrosis, pyknosis, lymphocyte infiltration, congestion of blood, dissolution of plasma membrane, and vacuolation were observed in the livers of pesticide-treated pigeons. The intestinal study showed the formation of goblet cells, villi rupturing, degeneration of serosa, necrosis, and pyknosis in treated groups. Renal alterations, dilation of renal tubules, reduction of glomerulus tissue, and edema were observed. This study manifests that the uncontrolled use of pesticides impairs ecosystems and poses a substantial health risk to wildlife and ultimately to human.