Can Time to Treatment Reduce In-Hospital Mortality and Morbidity Among Surgical and Nonsurgical Elderly Patients With Sepsis

• Published in: The American surgeon 2023-07, Vol.89 (7), p.3235-3237
• Main Authors: Wasfie, Tarik, Buzadzhi, Anna, Naisan, Mursal, Senger, Barbara, Memar, Shayan, Tangalos, Alexandra, Hella, Jennifer, Hood, Shannon, Barber, Kimberly
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Emergency Service, Hospital; Female; Hospital Mortality; Humans; Male; Middle Aged; Morbidity; Retrospective Studies; Sepsis - therapy; Time-to-Treatment
• ISSN: 0003-1348; 1555-9823
• DOI: 10.1177/00031348231157874

Sepsis mortality remains high and efforts to reduce it are continuing. We collected data from our patients presented to the emergency department (ED) with sepsis and performed a retrospective analysis of 1079 patients seen in the ED with sepsis during 2018 and 2020, before and after implementation of the new CDC protocol. Statistical analysis was performed using Student’s t-test and chi square test as well as Cox regression analysis. The patients were divided into pre-protocol (group 1) and post-protocol (group 2). A total of 1079 patients were included in the study. The mean age was 65 + 16.86 years, divided equally between gender (male 49%, female 51%). Patients with certain comorbidities showed statistically significant survival rate in the protocol group. The current protocol for sepsis when implemented will improve patients’ survival, in both surgical and medical patients and significantly in those with comorbid conditions.