Phyllanthus emblica fruits: a polyphenol-rich fruit with potential benefits for oral management

• Published in: Food & function 2023-08, Vol.14 (17), p.7738-7759
• Main Authors: Li, Gefei, Yu, Qiang, Li, Mengqi, Zhang, Dingkun, Yu, Ji, Yu, Xiaohan, Xia, Chenxi, Lin, Junzhi, Han, Li, Huang, Haozhou
• Format: Article
• Language: English
• Subjects: Alveolar bone; Anticancer properties; Bone cancer; Bone healing; Bone remodeling; Chemical composition; Damage prevention; Dietary supplements; Fruits; Glucose metabolism; Homology; Immunoregulation; Inflammation; Mucosa; Nutrients; Oral cancer; Oral hygiene; Oxidative stress; Periodontitis; Phyllanthus emblica; Planing; Radiation therapy; Saliva; Superoxide dismutase; Virulence; Vitamins; Wound healing
• ISSN: 2042-6496; 2042-650X
• DOI: 10.1039/d3fo01671d

The fruit of Linn., which mainly grows in tropical and subtropical regions, is well-known for its medicine and food homology properties. It has a distinctive flavor, great nutritional content, and potent antioxidant, anti-inflammatory, anti-cancer and immunoregulatory effects. According to an increasing amount of scientific and clinical evidence, this fruit shows significant potential for application and development in the field of oral health management. Through the supplementation of vitamins, superoxide dismutase (SOD) and other nutrients reduce virulence expression of various oral pathogens, prevent tissue and mucosal damage caused by oxidative stress, . fruit can promote saliva secretion, regulate the balance of the oral microecology, prevent and treat oral cancer early, promote alveolar bone remodeling and aid mucosal wound healing. Thus, it plays a specific role in the prevention and treatment of common oral disorders, producing surprising results. For instance, enhancing the effectiveness of scaling and root planing in the treatment of periodontitis, relieving mucosal inflammation caused by radiotherapy for oral cancer, and regulating the blood glucose metabolism to alleviate oral discomfort. Herein, we systematically review the latest research on the use of fruit in the management of oral health and examine the challenges and future research directions based on its chemical composition and characteristics.