Biliary atresia and liver transplantation in the United States: A contemporary analysis

Biliary atresia (BA) remains the number one indication for paediatric liver transplantation (LT) worldwide but is an uncommon indication for older LT recipients. The impact of recent donor allocation changes, pervasive organ shortage and evolving LT practices on the BA LT population is unknown. We i...

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Published in:Liver international 2023-10, Vol.43 (10), p.2198-2209
Main Authors: Anouti, Ahmad, Patel, Madhukar S, VanWagner, Lisa B, Lee, William M, Fung, John J, Cholankeril, George, Hwang, Christine S, Mufti, Arjmand R, Tujios, Shannan, Kerr, Thomas, Rich, Nicole E, Louissaint, Jeremy, Desai, Dev M, Vagefi, Parsia A, Hanish, Steven, Shah, Jigesh, Singal, Amit G, Cotter, Thomas G
Format: Article
Language:English
Subjects:
Biliary atresia
Grafting
Indication
Liver
Liver diseases
Liver transplantation
Regression analysis
Risk analysis
Survival
Transplantation
Transplants & implants
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Summary:Biliary atresia (BA) remains the number one indication for paediatric liver transplantation (LT) worldwide but is an uncommon indication for older LT recipients. The impact of recent donor allocation changes, pervasive organ shortage and evolving LT practices on the BA LT population is unknown. We identified patients who underwent LT between January 2010 and December 2021 using the UNOS database. We compared clinical outcomes between patients with BA and those with non-BA cholestatic liver disease. Groups were stratified by age,
ISSN:1478-3223
1478-3231
DOI:10.1111/liv.15689