Advances in Algomics technology: Application in wastewater treatment and biofuel production

• Published in: Bioresource technology 2023-11, Vol.387, p.129636-129636, Article 129636
• Main Authors: Kadri, Mohammad Sibtain, Singhania, Reeta Rani, Haldar, Dibyajyoti, Patel, Anil Kumar, Bhatia, Shashi Kant, Saratale, Ganesh, Parameswaran, Binod, Chang, Jo-Shu
• Format: Article
• Language: English
• Subjects: Algomics; Bioremediation; Circular bioeconomy; Microalgae; Sustainable goals
• ISSN: 0960-8524; 1873-2976
• DOI: 10.1016/j.biortech.2023.129636

[Display omitted] •The multi-omics approach provides enhanced regulation of the algal treatment system.•Metagenomics enables real-time monitoring of microbial dynamics and treatment system.•Transcriptomics offers insights into oxidative stress reactions against waste types.•Metabolomics helps identify specific metabolites associated with the degradation response.•The multi-omics role is promising in product enhancement and sustainable treatment. Advanced sustainable bioremediation is gaining importance with rising global pollution. This review examines microalgae's potential for sustainable bioremediation and process enhancement using multi-omics approaches. Recently, microalgae-bacterial consortia have emerged for synergistic nutrient removal, allowing complex metabolite exchanges. Advanced bioremediation requires effective consortium design or pure culture based on the treatment stage and specific roles. The strain potential must be screened using modern omics approaches aligning wastewater composition. The review highlights crucial research gaps in microalgal bioremediation. It discusses multi-omics advantages for understanding microalgal fitness concerning wastewater composition and facilitating the design of microalgal consortia based on bioremediation skills. Metagenomics enables strain identification, thereby monitoring microbial dynamics during the treatment process. Transcriptomics and metabolomics encourage the algal cell response toward nutrients and pollutants in wastewater. Multi-omics role is also summarized for product enhancement to make algal treatment sustainable and fit for sustainable development goals and growing circular bioeconomy scenario.