Clinical features and prognostic factors of elderly patients with mantle cell lymphoma

• Published in: Zhōnghuá xuèyèxué zázhì 2023-06, Vol.44 (6), p.495-500
• Main Authors: Hao, X Y, Yang, P, Zhang, W, Liu, H, Sun, X H, Xiao, X B, Wang, J W, Li, Z L, Li, L H, Wang, S Y, He, J, Li, X L, Jing, H M
• Format: Article
• Language: Chinese
• ISSN: 0253-2727
• DOI: 10.3760/cma.j.issn.0253-2727.2023.06.009

To examine the clinical characteristics and prognostic factors of elderly patients with mantle cell lymphoma (MCL) and the impact of nutrition and underlying diseases on the prognosis of elderly patients with MCL. retrospectively analyzed 255 elderly patients with MCL from 11 medical centers, including Peking University Third Hospital between January 2000 and February 2021. We analyzed clinical data, such as age, gender, Mantle Cell Lymphoma International Prognostic Index score, and treatment options, and performed univariate and multivariate prognostic analysis. We performed a comprehensive geriatric assessment on elderly MCL patients with medical records that included retraceable underlying disease and albumin levels, and we investigated the impact of basic nutrition and underlying disorders on MCL prognosis in the elderly. There were 255 senior individuals among the 795 MCL patients. Elderly MCL was more common in males (78.4%), with a median age of 69 yr (ages 65-88), and the majority (88.6%) were identif