Detergency of stainless steel surface soiled with human brain homogenate: an XPS study

In the detergency field of re-usable medical devices, a special attention is focused on the non conventional transmissible agent called prions which is a proteinaceous infectious agent. Few cleaning procedures are effective against prions and few techniques are available to study cleaning effectiven...

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Bibliographic Details
Published in:Applied surface science 2005-02, Vol.240 (1), p.204-213
Main Authors: Richard, M., Le Mogne, Th, Perret-Liaudet, A., Rauwel, G., Criquelion, J., De Barros, M.I., Cêtre, J.C., Martin, J.M.
Format: Article
Language:English
Subjects:
Applied sciences
Cross-disciplinary physics: materials science
rheology
Detergency
Exact sciences and technology
Human brain homogenate
Materials science
Medical device
Metals. Metallurgy
Physics
Proteins
Stainless steel
Surface cleaning, etching, patterning
Surface treatments
XPS
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Summary:In the detergency field of re-usable medical devices, a special attention is focused on the non conventional transmissible agent called prions which is a proteinaceous infectious agent. Few cleaning procedures are effective against prions and few techniques are available to study cleaning effectiveness with respect to proteins in general. In our study, X-ray photoelectron spectroscopy (XPS) has been used to evaluate the effectiveness of detergent formulations to remove proteins from stainless steel surface soiled with a brain homogenate (BH) from human origin. Our results showed that XPS is a reliable surface analysis technique to study chemical species remaining on surface and substrate properties after cleaning procedures. A semi-quantitative evaluation of the detergency effectiveness could also be performed.
ISSN:0169-4332
1873-5584
DOI:10.1016/j.apsusc.2004.06.090