Will artificial intelligence chatbots replace clinical pharmacologists? An exploratory study in clinical practice

Purpose Recently, there has been a growing interest in using ChatGPT for various applications in Medicine. We evaluated the interest of OpenAI chatbot (GPT 4.0) for drug information activities at Toulouse Pharmacovigilance Center. Methods Based on a series of 50 randomly selected questions sent to o...

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Bibliographic Details
Published in:European journal of clinical pharmacology 2023-10, Vol.79 (10), p.1375-1384
Main Authors: Montastruc, François, Storck, Wilhelm, de Canecaude, Claire, Victor, Léa, Li, Julien, Cesbron, Candice, Zelmat, Yoann, Barus, Romain
Format: Article
Language:English
Subjects:
Artificial intelligence
Biomedical and Life Sciences
Biomedicine
Causality
Chatbots
Clinical medicine
Drug interactions
Information services
Likert scale
Medical personnel
Patients
Pharmacists
Pharmacology
Pharmacology/Toxicology
Pharmacovigilance
Social networks
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Summary:Purpose Recently, there has been a growing interest in using ChatGPT for various applications in Medicine. We evaluated the interest of OpenAI chatbot (GPT 4.0) for drug information activities at Toulouse Pharmacovigilance Center. Methods Based on a series of 50 randomly selected questions sent to our pharmacovigilance center by healthcare professionals or patients, we compared the level of responses from the chatbot GPT 4.0 with those provided by specialists in pharmacovigilance. Results Chatbot answers were globally not acceptable. Responses to inquiries regarding the assessment of drug causality were not consistently precise or clinically meaningful. Conclusion The interest of chatbot assistance needs to be confirmed or rejected through further studies conducted in other pharmacovigilance centers.
ISSN:0031-6970
1432-1041
1432-1041
DOI:10.1007/s00228-023-03547-8