Oxidative stress affects the beginning of the growth of cancer cells through a variety of routes

Oxidative stress is a physiological condition that occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the cell's antioxidant defense system. ROS are highly reactive molecules that can cause damage to cellular structures such as DNA, proteins, and lipid...

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Published in:Pathology, research and practice research and practice, 2023-09, Vol.249, p.154664-154664, Article 154664
Main Authors: Saleh, Ebraheem Abdu Musad, Al-dolaimy, F., Qasim almajidi, Yasir, Baymakov, Sayfiddin, kader M, Mohammed Abdul, Ullah, Muhammad Ikram, Abbas, Ahmed hussien R., Khlewee, Ibrahim Hammoud, Bisht, Yashwant Singh, Alsaalamy, Ali Hashiem
Format: Article
Language:English
Subjects:
Cancer
Oxidative stress
Therapeutic approaches
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Summary:Oxidative stress is a physiological condition that occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the cell's antioxidant defense system. ROS are highly reactive molecules that can cause damage to cellular structures such as DNA, proteins, and lipids. the regulation of ROS levels and the antioxidant defense system is crucial for cancer prevention and treatment. Strategies to enhance antioxidant defenses or induce oxidative stress selectively in cancer cells are being developed as potential therapeutic approaches. targeting oxidative stress in cancer treatment is an active area of research with several potential therapeutic approaches being investigated. Developing selective and effective therapies that target oxidative stress in cancer cells while sparing normal cells will be crucial for improving cancer treatment outcomes.
ISSN:0344-0338
1618-0631
DOI:10.1016/j.prp.2023.154664