Influenza A (H1N1) virus induced long‐term remission in a refractory acute myeloid leukaemia

You et al. present an extraordinary case of a refractory acute myeloid leukaemia (AML) patient who achieved long‐term complete remission after infection with Influenza A. Using mouse models, the researchers examined the underlying immunological mechanisms and discovered a decrease in leukaemia proli...

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Bibliographic Details
Published in:British journal of haematology 2023-08, Vol.202 (4), p.713-714
Main Authors: Miladinovic, Milica, Klusmann, Jan‐Henning
Format: Article
Language:English
Subjects:
Acute myeloid leukemia
Animal models
Hematology
Influenza A
influenza A virus
long‐term remission
Remission
Viruses
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Summary:You et al. present an extraordinary case of a refractory acute myeloid leukaemia (AML) patient who achieved long‐term complete remission after infection with Influenza A. Using mouse models, the researchers examined the underlying immunological mechanisms and discovered a decrease in leukaemia proliferation and improved survival in Influenza‐A virus‐infected mice. These results indicate the potential therapeutic relevance of Influenza A in the treatment of haematological cancers. Commentary on: You et al. Influenza A (H1N1) virus induced long‐term remission in a refractory acute myeloid leukemia. Br J Haematol 2023;202:745–748.
ISSN:0007-1048
1365-2141
DOI:10.1111/bjh.18911