Feeding artery: a valuable feature for differentiation of regenerative nodule, dysplastic nodules and small hepatocellular carcinoma in CEUS LI-RADS

Objective To investigate whether the feeding artery (FA) feature can aid in discriminating small hepatocellular carcinoma (HCC) using the contrast-enhanced ultrasound (CEUS) Liver Imaging Reporting and Data System (LI-RADS) from precancerous lesions. Methods Between June 2017 and May 2021, a total o...

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Bibliographic Details
Published in:European radiology 2024-02, Vol.34 (2), p.745-754
Main Authors: Wu, Jiapeng, Zhao, Qinxian, Wang, Yuling, Xiao, Fan, Cai, Wenjia, Liu, Sisi, Du, Zhicheng, Yu, Xiaoling, Liu, Fangyi, Yu, Jie, Liang, Ping
Format: Article
Language:English
Subjects:
Biomarkers
Data systems
Diagnostic Radiology
Diagnostic systems
Differentiation
Feeding
Hepatocellular carcinoma
Imaging
Internal Medicine
Interventional Radiology
Lesions
Liver
Liver cancer
Medical imaging
Medicine
Medicine & Public Health
Neuroradiology
Nodules
Radiology
Ultrasound
Veins & arteries
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Summary:Objective To investigate whether the feeding artery (FA) feature can aid in discriminating small hepatocellular carcinoma (HCC) using the contrast-enhanced ultrasound (CEUS) Liver Imaging Reporting and Data System (LI-RADS) from precancerous lesions. Methods Between June 2017 and May 2021, a total of 347 patients with 351 precancerous liver lesions or small HCCs who underwent CEUS were enrolled. Two independent radiologists assigned LI-RADS categories to all lesions and assessed the presence of the FA feature, which was used as an ancillary feature to either upgrade or downgrade the LI-RADS category. The diagnostic performance of CEUS LI-RADS, both with and without the FA feature, was evaluated based on accuracy, sensitivity, specificity, positive predictive value, and negative predictive value. Results The FA feature was found to be more prevalent in HCC (85.54%, p  
ISSN:1432-1084
0938-7994
1432-1084
DOI:10.1007/s00330-023-10006-6